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Enhanced sensitivity of Escherichia coli umuC to photodynamic inactivation by angelicin (isopsoralen).大肠杆菌umuC对补骨脂素（异补骨脂素）光动力灭活的敏感性增强。
J Bacteriol. 1985 Jun;162(3):1307-10. doi: 10.1128/jb.162.3.1307-1310.1985.
2
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Suppressible base substitution mutations induced by angelicin (isopsoralen) in the Escherichia coli lacI gene: implications for the mechanism of SOS mutagenesis.当归素（异补骨脂素）诱导的大肠杆菌lacI基因中的可抑制碱基置换突变：对SOS诱变机制的启示
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J Photochem Photobiol B. 1989 Aug;3(4):497-507. doi: 10.1016/1011-1344(89)80075-2.
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Photodynamic inactivation and mutagenesis by angelicin (isopsoralen) or thiopyronin (methylene red) in wild-type and repair-deficient strains of bacteriophage T4.野生型和修复缺陷型噬菌体T4菌株中当归素（异补骨脂素）或硫代吡咯宁（亚甲蓝）的光动力失活与诱变作用
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An inducible pathway is required for mutagenesis in Salmonella typhimurium LT2.鼠伤寒沙门氏菌LT2中的诱变需要一条可诱导途径。
J Bacteriol. 1987 Jun;169(6):2885-8. doi: 10.1128/jb.169.6.2885-2888.1987.

本文引用的文献

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Induction of Mutations in a Bacterial Virus.细菌病毒中突变的诱导
Proc Natl Acad Sci U S A. 1953 Jul;39(7):628-36. doi: 10.1073/pnas.39.7.628.
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Acetylornithinase of Escherichia coli: partial purification and some properties.大肠杆菌的乙酰鸟氨酸酶：部分纯化及某些性质
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Psoralen photochemistry and nucleic acid structure.补骨脂素光化学与核酸结构
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Psoralen-deoxyribonucleic acid photoreaction. Characterization of the monoaddition products from 8-methoxypsoralen and 4,5'8-trimethylpsoralen.补骨脂素 - 脱氧核糖核酸光反应。8 - 甲氧基补骨脂素和4,5',8 - 三甲基补骨脂素单加成产物的特性
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Sensitivity of DNA repair-deficient strains of Escherichia coli K-12 to various furocoumarins and near-ultraviolet radiation.
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DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli.DNA损伤剂刺激大肠杆菌中特定基因座的基因表达。
Proc Natl Acad Sci U S A. 1980 May;77(5):2819-23. doi: 10.1073/pnas.77.5.2819.
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Identification of plasmid (pKM101)-coded proteins involved in mutagenesis and UV resistance.鉴定参与诱变和紫外线抗性的质粒（pKM101）编码蛋白。
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Mutagenesis by neocarzinostatin in Escherichia coli and Salmonella typhimurium: requirement for umuC+ or plasmid pKM101.新制癌菌素在大肠杆菌和鼠伤寒沙门氏菌中诱导的诱变作用：对umuC+或质粒pKM101的需求
J Bacteriol. 1980 Nov;144(2):656-60. doi: 10.1128/jb.144.2.656-660.1980.
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Base substitution mutations induced by metabolically activated aflatoxin B1.由代谢活化的黄曲霉毒素B1诱导的碱基置换突变。
Proc Natl Acad Sci U S A. 1983 May;80(9):2695-8. doi: 10.1073/pnas.80.9.2695.
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Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli.大肠杆菌中的诱变作用及对脱氧核糖核酸损伤的诱导反应
Microbiol Rev. 1984 Mar;48(1):60-93. doi: 10.1128/mr.48.1.60-93.1984.

大肠杆菌umuC对补骨脂素（异补骨脂素）光动力灭活的敏感性增强。

Enhanced sensitivity of Escherichia coli umuC to photodynamic inactivation by angelicin (isopsoralen).

作者信息

Miller S S, Eisenstadt E

出版信息

J Bacteriol. 1985 Jun;162(3):1307-10. doi: 10.1128/jb.162.3.1307-1310.1985.

DOI:10.1128/jb.162.3.1307-1310.1985
PMID:3888964
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC215921/
Abstract

Escherichia coli umuC cells were inactivated four times more rapidly than umuC+ cells by angelicin (a monofunctional psoralen) plus near-UV irradiation. With other DNA-damaging treatments, either no or much smaller differences in sensitivity were observed. These results show that functions associated with the UmuC+ phenotype contribute to the repair (or tolerance) of some categories of DNA damage more efficiently than others.

摘要

与umuC+细胞相比，大肠杆菌umuC细胞被当归素（一种单功能补骨脂素）加近紫外辐射灭活的速度快四倍。对于其他DNA损伤处理，未观察到敏感性差异或差异小得多。这些结果表明，与UmuC+表型相关的功能比其他功能更有效地促进某些类型DNA损伤的修复（或耐受）。