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新冠后(post-COVID)条件下患者的肺康复方案和/或呼吸肌训练的有效性:系统评价。

Effectiveness of pulmonary rehabilitation programmes and/or respiratory muscle training in patients with post-COVID conditions: a systematic review.

机构信息

Department of Physiotherapy, Faculty of Health Science, University of Malaga, Málaga, 29071, Spain.

Department of Nursing and Physiotherapy, University of Cadiz, Cádiz, Spain.

出版信息

Respir Res. 2024 Jun 19;25(1):248. doi: 10.1186/s12931-024-02857-4.

DOI:10.1186/s12931-024-02857-4
PMID:38890699
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11186160/
Abstract

BACKGROUND

The term "post-COVID-19 condition" refers to the symptomatology that appears between four to twelve weeks after Covid-19 infection. These symptoms can persist for weeks or even months, significantly diminishing the quality of life for affected individuals. The primary objective of this study was to assess the effectiveness of pulmonary rehabilitation programs and/or respiratory muscle training on respiratory sequelae in patients with post-COVID condition.

METHODS

The literature search was conducted in the following databases: PubMed, PEDro, Embase, Cochrane, Scopus, and Web of Science. Randomized clinical trials were included in which participants were aged 18 years or older. Articles were excluded if at least one of the therapies did not involve pulmonary rehabilitation or respiratory muscle training, if the participants were COVID positive, if studies lacked results, and finally, if interventions were conducted without supervision or at home. This review only encompasses supervised non-virtual interventions. This study adheres to the PRISMA statement and has been registered in the PROSPERO database (CRD42023433843).

RESULTS

The outcomes obtained in the included studies are assessed across the following variables: Exercise capacity using the 6-minute walk test, Dyspnea, fatigue, Pulmonary function, Maximum inspiratory pressure, and Quality of life.

CONCLUSION

Despite the absence of a specific treatment at present, it was evident from this review that a well-structured pulmonary rehabilitation program that incorporates both aerobic and muscular strength exercises along with techniques and inspiratory muscle exercises was the most effective form of treatment.

摘要

背景

“新冠后状况”一词是指感染新冠病毒后 4 至 12 周出现的症状。这些症状可能持续数周甚至数月,显著降低患者的生活质量。本研究的主要目的是评估肺康复计划和/或呼吸肌训练对新冠后状况患者的呼吸后遗症的疗效。

方法

文献检索在以下数据库进行:PubMed、PEDro、Embase、Cochrane、Scopus 和 Web of Science。纳入的随机临床试验中,参与者年龄在 18 岁或以上。如果至少有一种疗法不涉及肺康复或呼吸肌训练,如果参与者新冠病毒检测呈阳性,如果研究缺乏结果,最后,如果干预措施是在没有监督或在家中进行的,则排除这些文章。本综述仅涵盖有监督的非虚拟干预。本研究遵循 PRISMA 声明,并已在 PROSPERO 数据库(CRD42023433843)中注册。

结果

纳入研究的结果通过以下变量进行评估:使用 6 分钟步行测试评估运动能力、呼吸困难、疲劳、肺功能、最大吸气压力和生活质量。

结论

尽管目前尚无特定治疗方法,但本综述表明,结合有氧运动和肌肉力量训练以及技术和吸气肌训练的结构化肺康复计划是最有效的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed34/11186160/a1d6e05a7775/12931_2024_2857_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed34/11186160/3c430d67f929/12931_2024_2857_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed34/11186160/81874961db57/12931_2024_2857_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed34/11186160/a1d6e05a7775/12931_2024_2857_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed34/11186160/3c430d67f929/12931_2024_2857_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed34/11186160/81874961db57/12931_2024_2857_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed34/11186160/a1d6e05a7775/12931_2024_2857_Fig3_HTML.jpg

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Pulmonary function abnormality in patients recovered from Covid 19 pneumonia, in a tertiary care hospital in India.印度一家三级护理医院中新冠病毒肺炎康复患者的肺功能异常情况。
Lung India. 2023 May-Jun;40(3):248-252. doi: 10.4103/lungindia.lungindia_15_23.
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Inpatient post-COVID-19 rehabilitation program featuring virtual reality-Preliminary results of randomized controlled trial.
新冠肺炎后住院康复计划采用虚拟现实技术-随机对照试验的初步结果。
Front Public Health. 2023 Feb 6;11:1121554. doi: 10.3389/fpubh.2023.1121554. eCollection 2023.
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The development of COVID-19 treatment.COVID-19 治疗的发展。
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Long COVID: major findings, mechanisms and recommendations.长新冠:主要发现、机制和建议。
Nat Rev Microbiol. 2023 Mar;21(3):133-146. doi: 10.1038/s41579-022-00846-2. Epub 2023 Jan 13.
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