Riphah College of Rehabilitation Sciences, Riphah International University, Lahore Campus, Lahore, 54600, Pakistan.
University of Management and Technology, Lahore, Pakistan.
BMC Womens Health. 2024 Jun 19;24(1):354. doi: 10.1186/s12905-024-03203-y.
The sex steroid hormones fluctuate during the menstrual cycle, which affects the strength and postural stability of females and leads to injuries and risk of falls. These hormones may be modulated by exercise to impact the overall health of females.
To determine the effects of exercise on sex steroid hormones in eumenorrheic females.
This review was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA) guidelines in Lahore, Pakistan. The full-length articles were searched using these databases/search engines (PubMed, Web of Science and Google Scholar, Sci-Hub). Randomized controlled trials along with single group experimental studies were also included. All types of exercises were compared with no exercise in the control group. The Cochrane Risk of Bias assessment tool assessed and screened the articles. The data were then analyzed. The primary outcomes were the levels of estrogen, progesterone and testosterone.
Eleven studies were included (5 randomized controlled trials and 6 quasi-experimental studies). The effects of exercise on free estradiol concentration and serum progesterone level were not significant [p = 0.37 (SMD = 0.33, 95% CI = 0.14 to 0.74, I = 0%) and p = 0.84 (S.D= -0.65, C.I= -6.92 to 5.62, I = 94%)] respectively, whereas, the effects on testosterone levels were significant [p value < 0.00001 (M.D = 0.89, 95% C.I= -2.16 to 3.95, I = 94%)].
A blinded randomized controlled trial should be conducted in which a structured approach should be followed by women along with warm-ups, cool down and rest intervals.
The systematic review was registered prospectively on PROSPERO with registration number CRD42023473767.
女性的性激素在月经周期中波动，这会影响她们的力量和姿势稳定性，导致受伤和跌倒的风险增加。这些激素可能会通过运动得到调节，从而影响女性的整体健康。
确定运动对月经正常女性性激素的影响。
本研究在巴基斯坦拉合尔按照系统评价和荟萃分析的首选报告项目（PRISMA）指南进行。使用这些数据库/搜索引擎（PubMed、Web of Science 和 Google Scholar、Sci-Hub）搜索全文文章。还纳入了随机对照试验和单组实验研究。对照组中所有类型的运动均与不运动进行比较。使用 Cochrane 偏倚风险评估工具对文章进行评估和筛选。然后对数据进行分析。主要结局指标是雌激素、孕激素和睾酮水平。
纳入了 11 项研究（5 项随机对照试验和 6 项准实验研究）。运动对游离雌二醇浓度和血清孕激素水平的影响不显著[p=0.37（SMD=0.33，95%CI=0.14 至 0.74，I=0%）和 p=0.84（S.D=-0.65，C.I=-6.92 至 5.62，I=94%）]，而对睾酮水平的影响则显著[p 值<0.00001（M.D=0.89，95%CI=-2.16 至 3.95，I=94%）]。
应该进行一项盲法随机对照试验，其中女性应遵循结构化的方法，包括热身、冷却和休息间隔。
该系统评价已在 PROSPERO 上进行了前瞻性注册，注册号为 CRD42023473767。
