An Sang-Mee, Chae Ji Seon, Lee Hyun Jung, Cho Sooyoung, Im Jiwoong
Department of Anesthesiology and Pain Medicine, Ewha Womans University Seoul Hospital, Seoul 07804, Republic of Korea.
Department of Anesthesiology and Pain Medicine, College of Medicine, Ewha Womans University, Seoul 07804, Republic of Korea.
J Clin Med. 2024 May 25;13(11):3100. doi: 10.3390/jcm13113100.
: The psoas: lumbar vertebral index (PLVI) is a simple and convenient measure to assess central sarcopenia. Recent studies have utilized the psoas area to indirectly assess sarcopenia and frailty, exploring their associations with various health outcomes. This study aims to investigate the relationship between the PLVI and postherpetic neuralgia (PHN) in patients aged 60 years and above following a herpes zoster (HZ) infection. We conducted a retrospective analysis of data from 351 patients (≥60 years) who developed HZ between January 2019 and December 2023; the patients were divided into two groups based on the presence or absence of PHN after HZ onset. The analyses using receiver operating characteristic curves revealed a value for the area under the curve of 0.813 for PLVI and 0.769 for the modified frailty index (mFI). In a multivariate logistic regression analysis, numerical rating scale scoring, a low PLVI, and a greater number of categorical mFI variables (adjusted odds ratio: 1.30, 3.27, and 2.46, respectively) were found to be significant independent predictors of PHN. Our findings highlight the association between a low PLVI and PHN in an older population. The PLVI may have potential as a predictive tool for PHN in older patients with HZ, but further research is needed to confirm these results.
腰大肌-腰椎指数（PLVI）是评估中枢性肌肉减少症的一种简单便捷的指标。近期研究利用腰大肌面积间接评估肌肉减少症和衰弱，并探究它们与各种健康结局的关联。本研究旨在调查60岁及以上带状疱疹（HZ）感染患者中PLVI与带状疱疹后神经痛（PHN）之间的关系。我们对2019年1月至2023年12月期间发生HZ的351例（≥60岁）患者的数据进行了回顾性分析；根据HZ发作后是否存在PHN将患者分为两组。使用受试者工作特征曲线进行的分析显示，PLVI的曲线下面积值为0.813，改良衰弱指数（mFI）的曲线下面积值为0.769。在多因素逻辑回归分析中，数字评分量表评分、低PLVI以及更多的mFI分类变量（调整后的比值比分别为1.30、3.27和2.46）被发现是PHN的显著独立预测因素。我们的研究结果突出了老年人群中低PLVI与PHN之间的关联。PLVI可能有潜力作为老年HZ患者PHN的预测工具，但需要进一步研究来证实这些结果。
