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评估新冠病毒肺炎重症监护病房幸存者的心理健康结果:测量工具的范围综述

Evaluating Mental Health Outcomes in COVID-19 ICU Survivors: A Scoping Review of Measurement Tools.

作者信息

T'ng Kimberly, Kenardy Justin, Hartanto Andree

机构信息

School of Psychology, University of Queensland, Brisbane, QLD 4072, Australia.

School of Social Sciences, Singapore Management University, 10 Canning Rise, Level 5, Singapore 179873, Singapore.

出版信息

J Clin Med. 2024 May 29;13(11):3191. doi: 10.3390/jcm13113191.

Abstract

The objective of this scoping review was to map the range of measurement tools used to study the prevalence of common mental health conditions in COVID-19 ICU survivors. Increased rates of admission to and survivorship from intensive care units (ICUs) have been observed in recent years, particularly during the global pandemic. ICU patients are at a higher risk of developing depressive, anxiety, and PTSD symptoms. Due to the high burden of disease, an accurate understanding of long-term mental health challenges for this population is key. Unfortunately, there is significant variability in reported prevalence rates. Heterogeneity in measurement tools potentially contribute to this. Studies were eligible if they (a) reported mental health outcomes of adult patients diagnosed with COVID-19 and admitted to an ICU, (b) used standardised mental health outcome measures, and (3) were peer-reviewed. Searches were conducted in PubMed, PsycInfo, and Scopus. The initial search retrieved 1234 publications. After de-duplication and title and abstract screening, 72 full-text articles were examined for eligibility and 44 articles were excluded, leaving 28 eligible studies. Reference lists of the eligible studies were screened, and four other studies were added. 32 studies were ultimately included in this review. Significant heterogeneity of measurement tools and clinical thresholds were observed. Only 6.25% of the studies compared changes in mental health outcomes to baseline measurements. Between five and nine unique measurement tools were used to study depression, anxiety, and PTSD, respectively. Studies were also observed to use up to 19 different thresholds to establish the prevalence of PTSD. The heterogeneity of measurement tools and thresholds continues to confound prevalence rate estimations of mental health complications post-ICU admission. Future research will benefit from consistency in the use of recommended outcome measures and the use of psychometrically comparable cut-off points between key measures.

摘要

本综述的目的是梳理用于研究新冠疫情期间入住重症监护病房(ICU)的幸存者中常见心理健康状况患病率的一系列测量工具。近年来,尤其是在全球疫情期间,重症监护病房的入院率和存活率有所上升。ICU患者出现抑郁、焦虑和创伤后应激障碍(PTSD)症状的风险更高。由于疾病负担沉重,准确了解这一人群的长期心理健康挑战至关重要。不幸的是,报告的患病率存在显著差异。测量工具的异质性可能是造成这种情况的原因之一。符合以下条件的研究纳入本综述:(a)报告了确诊感染新冠病毒并入住ICU的成年患者的心理健康结果;(b)使用了标准化的心理健康结果测量方法;(c)经过同行评审。检索了PubMed、PsycInfo和Scopus数据库。初步检索共获得1234篇文献。经过去重、标题和摘要筛选后,对72篇全文进行了资格审查,排除了44篇文章,最终纳入28项符合条件的研究。对符合条件的研究的参考文献列表进行了筛选,又增加了4项研究。最终本综述纳入了32项研究。观察到测量工具和临床阈值存在显著异质性。只有6.25%的研究将心理健康结果的变化与基线测量进行了比较。分别使用了5至9种不同的测量工具来研究抑郁、焦虑和创伤后应激障碍。研究还发现,确定创伤后应激障碍患病率时使用了多达19种不同的阈值。测量工具和阈值的异质性继续混淆了ICU入院后心理健康并发症患病率的估计。未来的研究将受益于使用推荐的结果测量方法的一致性,以及关键测量方法之间在心理测量学上可比的临界点的使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00ef/11172430/0566005ba6a7/jcm-13-03191-g001.jpg

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