高级别脑膜瘤的外科治疗
Surgical Management of High-Grade Meningiomas.
作者信息
Pacult Mark A, Przybylowski Colin J, Raza Shaan M, DeMonte Franco
机构信息
Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA.
Division of Neurosurgery, Fukushima Brain Tumor Center, Raleigh Neurosurgical Clinic, Raleigh, NC 27609, USA.
出版信息
Cancers (Basel). 2024 May 23;16(11):1978. doi: 10.3390/cancers16111978.
Maximal resection with the preservation of neurological function are the mainstays of the surgical management of high-grade meningiomas. Surgical morbidity is strongly associated with tumor size, location, and invasiveness, whereas patient survival is strongly associated with the extent of resection, tumor biology, and patient health. A versatile microsurgical skill set combined with a cogent multimodality treatment plan is critical in order to achieve optimal patient outcomes. Continued refinement in surgical techniques in conjunction with directed radiotherapeutic and medical therapies will define future treatment.
在保留神经功能的前提下进行最大程度切除是高级别脑膜瘤外科治疗的主要手段。手术并发症与肿瘤大小、位置及侵袭性密切相关，而患者生存率则与切除范围、肿瘤生物学特性及患者健康状况密切相关。一套通用的显微外科技能与一个有说服力的多模态治疗方案相结合对于实现最佳患者预后至关重要。手术技术的持续改进以及有针对性的放射治疗和药物治疗将决定未来的治疗方向。
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