Al Taweel Bader, Cassese Gianluca, Khayat Salah, Chazal Maurice, Navarro Francis, Guiu Boris, Panaro Fabrizio
Department of Digestive Surgery and Liver Transplantation, Montpellier University Hospital, 34090 Montpellier, France.
Department of Clinical Medicine and Surgery, Division of Minimally Invasive and Robotic HPB Surgery and Transplantation Service, University of Naples "Federico II", 80131 Naples, Italy.
Cancers (Basel). 2024 May 23;16(11):1982. doi: 10.3390/cancers16111982.
: Liver venous deprivation (LVD) is a recent radiological technique that has shown promising results on Future Remnant Liver (FRL) hypertrophy. The aim of this retrospective study is to compare the segmentary hypertrophy of the FRL after LVD and after portal vein embolization (PVE). : Patients undergoing PVE or LVD between April 2015 and April 2020 were included. The segmentary volumes (seg 4, seg2+3 and seg1) were assessed before and after the radiological procedure. : Forty-four patients were included: 26 undergoing PVE, 10 LVD and 8 eLVD. Volume gain of both segment 1 and segments 2+3 was significantly higher after LVD and eLVD than after PVE (segment 1: 27.33 ± 35.37 after PVE vs. 38.73% ± 13.47 after LVD and 79.13% ± 41.23 after eLVD, = 0.0080; segments 2+3: 40.73% ± 40.53 after PVE vs. 45.02% ± 21.53 after LVD and 85.49% ± 45.51 after eLVD, = 0.0137), while this was not true for segment 4. FRL hypertrophy was confirmed to be higher after LVD and eLVD than after PVE (33.53% ± 21.22 vs. 68.63% ± 42.03 vs. 28.11% ± 28.33, respectively, = 0.0280). : LVD and eLVD may induce greater hypertrophy of segment 1 and segments 2+3 when compared to PVE.
肝静脉阻断术（LVD）是一种最新的放射学技术，已在未来剩余肝脏（FRL）肥大方面显示出有前景的结果。本回顾性研究的目的是比较LVD和门静脉栓塞术（PVE）后FRL的节段性肥大情况。纳入2015年4月至2020年4月期间接受PVE或LVD的患者。在放射学操作前后评估节段体积（第4段、第2+3段和第1段）。纳入44例患者：26例行PVE，10例行LVD，8例行eLVD。LVD和eLVD后第1段和第2+3段的体积增加显著高于PVE后（第1段：PVE后为27.33±35.37，LVD后为38.73%±13.47，eLVD后为79.13%±41.23，P = 0.0080；第2+3段：PVE后为40.73%±40.53，LVD后为45.02%±21.53，eLVD后为85.49%±45.51，P = 0.0137），而第4段并非如此。证实LVD和eLVD后FRL肥大高于PVE后（分别为33.53%±21.22、68.63%±42.03和28.11%±28.33，P = 0.0280）。与PVE相比，LVD和eLVD可能诱导第1段和第2+3段更大程度的肥大。
