Marsot-Dupuch K, Martin-Lalardrie B, Conte J, Tubiana J M, Lelloucheazan M
J Radiol. 1985 Feb;66(2):91-7.
Leydig cell tumors arise from the gonadal stroma and represent two or three per cent of all testicular tumors. They may occur at any age in contrast with germinal tumor. In adults, about 20 per cent occur with endocrine disturbance: gynecomastia or impotence. Ten per cent are malignant and few cases are bilateral. They are small, yellow, brown tumor. Reinke's crystals are observed in 50 per cent and are pathognomonic. They present no necrosis no hemorrhage, no cyst. A benign tumor is difficult to distinguish from a malignant tumor. A vascular and capsular invasion, an infiltrative margin, a bilateral or multiple tumors must evoke a malignant case. Cryptorchidism, even corrected seems to be partly responsible in tumor induction. Ultrasonography can help for a precocious and reliable diagnosis of tumors, specially in case of occult tumors (2 cases). It also helps to survey the controlateral testis (bilateral tumor: 1 case).
睾丸间质细胞瘤起源于性腺间质，占所有睾丸肿瘤的2%至3%。与生殖细胞肿瘤不同，它们可发生于任何年龄。在成年人中，约20%的病例伴有内分泌紊乱：男性乳房发育或阳痿。10%为恶性，少数病例为双侧性。它们是小的、黄色或棕色肿瘤。50%的病例可观察到雷氏晶体，具有诊断意义。它们无坏死、无出血、无囊肿。良性肿瘤与恶性肿瘤难以区分。血管和包膜侵犯、浸润性边缘、双侧或多发肿瘤必须考虑恶性情况。隐睾症即使已矫正，似乎也在一定程度上参与肿瘤的诱发。超声检查有助于早期且可靠地诊断肿瘤，特别是在隐匿性肿瘤（2例）的情况下。它还有助于检查对侧睾丸（双侧肿瘤：1例）。
