Gupta S K, Francis I M, Sheikh Z A, al-Rubah N A, Das D K
Department of Pathology, Faculty of Medicine, University of Kuwait.
Acta Cytol. 1994 Mar-Apr;38(2):252-6.
Fine needle aspiration cytologic findings in a Leydig cell tumor of the testis are described. Besides the rarity of case reports on fine needle aspiration cytologic diagnosis of this tumor, the present case was of interest because of the finding of numerous intranuclear and intracytoplasmic Reinke's crystals as well as some lying free between the cells. In a few cells the intranuclear crystals were seen to orient themselves in a row, with a nipplelike protrusion of the nuclear membrane as if being pushed by the crystals. Besides the well-formed crystals, many nuclei showed irregular, thin, groovelike spaces that may have been earlier stages of crystal formation. These findings suggested the intranuclear formation of Reinke's crystals. Extranuclear crystals were seen to fuse in pairs and hence to appear thicker than the intranuclear crystals. The crystals lying free between the cells also showed a linear arrangement in places. The crystals were more numerous with May-Grünwald-Giemsa (MGG) staining. Intranuclear crystals were seen only in MGG-stained smears.
本文描述了睾丸间质细胞瘤的细针穿刺细胞学检查结果。除了该肿瘤细针穿刺细胞学诊断的病例报告罕见外，本病例因发现大量核内和胞质内的雷氏晶体以及一些游离于细胞之间的晶体而备受关注。在少数细胞中，可见核内晶体排成一排，核膜有乳头状突起，仿佛被晶体推动。除了形成良好的晶体外，许多细胞核还显示出不规则、细的、沟状的间隙，这可能是晶体形成的早期阶段。这些发现提示雷氏晶体在核内形成。核外晶体可见成对融合，因此看起来比核内晶体更厚。细胞间游离的晶体在某些部位也呈线性排列。用美蓝-伊红染色（MGG）时晶体数量更多。核内晶体仅在MGG染色涂片中可见。
