初潮过早是韩国年轻女性身材矮小的一个风险因素：一项流行病学研究。
Early Menarche is a Risk Factor for Short Stature in Young Korean Females: An Epidemiologic Study.
作者信息
Kang Sol, Kim Yoon Mo, Lee Jun Ah, Kim Dong Ho, Lim Jung Sub
机构信息
Korea Cancer Center Hospital, Department of Pediatrics, Seoul, Republic of Korea
出版信息
J Clin Res Pediatr Endocrinol. 2019 Sep 3;11(3):234-239. doi: 10.4274/jcrpe.galenos.2018.2018.0274. Epub 2019 Jan 3.
OBJECTIVE
To assess the association between age at menarche and adult height [and body mass index (BMI)] in young Korean females and also to investigate whether early menarche (<12 years) is a risk factor for short stature and obesity in young Korean females.
METHODS
Data on 1148 females aged 18-30 years and 612 mother (612 pairs of mothers and daughters) from the 6 Korea National Health and Nutrition Examination Survey (2013-2015) were analyzed.
RESULTS
Among 1148 females, 256 (22.3%) had early menarche. Their stature was approximately 0.445 cm shorter when menarche had occurred one year earlier. The prevalence of short stature (≤153 cm) and obesity (BMI ≥25) was higher in females with early menarche compared to those with later menarche (short stature: 10.5% vs 6.4%, obesity; 20.7% vs 13.1%, all p<0.001). In multivariate regression, the odds ratio (OR) for short stature was 2.62 [95% confidence interval (CI): 1.26-5.44] after adjusting for current age and mother’s height. OR for obesity was 1.74 (95% CI: 0.98-3.07) after adjusting for age and maternal BMI.
CONCLUSION
Final height in girls is influenced by age of menarche. Early menarche increased the risk for adult short stature in young Korean females.
目的
评估韩国年轻女性初潮年龄与成年身高[及体重指数（BMI）]之间的关联，并调查初潮早（<12岁）是否为韩国年轻女性身材矮小和肥胖的危险因素。
方法
分析了来自韩国国家健康与营养检查调查（2013 - 2015年）的1148名18 - 30岁女性及612名母亲（612对母女）的数据。
结果
在1148名女性中，256名（22.3%）初潮早。初潮提前一年发生时，她们的身高约矮0.445厘米。与初潮晚的女性相比，初潮早的女性身材矮小（≤153厘米）和肥胖（BMI≥25）的患病率更高（身材矮小：10.5%对6.4%，肥胖：20.7%对13.1%，均p<0.001）。在多变量回归分析中，调整当前年龄和母亲身高后，身材矮小的比值比（OR）为2.62 [95%置信区间（CI）：1.26 - 5.44]。调整年龄和母亲BMI后，肥胖的OR为1.74（95% CI：0.98 - 3.07）。
结论
女孩的最终身高受初潮年龄影响。初潮早会增加韩国年轻女性成年后身材矮小的风险。
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