大白菜中的一种诱变前体，吲哚 - 3 - 乙腈，经亚硝酸盐处理后会变成诱变剂。

A mutagen precursor in Chinese cabbage, indole-3-acetonitrile, which becomes mutagenic on nitrite treatment.

作者信息

Wakabayashi K, Nagao M, Ochiai M, Tahira T, Yamaizumi Z, Sugimura T

出版信息

Mutat Res. 1985 May-Jun;143(1-2):17-21. doi: 10.1016/0165-7992(85)90098-3.

Abstract

After treatment with nitrite, Chinese cabbage showed direct-acting mutagenicity on Salmonella typhimurium TA100 inducing 3100 revertants per g. One of the mutagen precursors that became mutagenic after nitrite treatment was isolated, and identified as indole-3-acetonitrile. After treatment with nitrite, 1 mg of indole-3-acetonitrile induced 17 400 revertants of TA100 and 21 000 revertants of TA98 without S9 mix.

摘要

用亚硝酸盐处理后，大白菜对鼠伤寒沙门氏菌TA100表现出直接致突变性，每克诱导3100个回复突变体。分离出一种经亚硝酸盐处理后具有致突变性的诱变前体，并鉴定为吲哚-3-乙腈。用亚硝酸盐处理后，1毫克吲哚-3-乙腈在无S9混合物的情况下诱导TA100的17400个回复突变体和TA98的21000个回复突变体。