• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Mutagenicity arising from boiled rice on treatment with nitrous acid.用亚硝酸处理后的米饭产生的致突变性。
Jpn J Cancer Res. 1989 Nov;80(11):1021-3. doi: 10.1111/j.1349-7006.1989.tb02252.x.
2
Use of nitrous acid-dependent decrease in mutagenicity as an indication of the presence of mutagenic primary aromatic amines. Non-specific reactions with phenols and benzo[alpha]pyrene.使用亚硝酸依赖的致突变性降低作为诱变原发性芳香胺存在的指标。与酚类和苯并[a]芘的非特异性反应。
Mutat Res. 1981 Jun;82(1):59-67. doi: 10.1016/0027-5107(81)90138-x.
3
The bacterial mutagenicity of three naturally occurring indoles after reaction with nitrous acid.三种天然存在的吲哚与亚硝酸反应后的细菌致突变性。
Mutat Res. 1983 Oct;124(1):35-51. doi: 10.1016/0165-1218(83)90183-0.
4
Effects of Maillard reaction products on mutagen formation in boiled pork juice.
Mutagenesis. 1995 May;10(3):179-83. doi: 10.1093/mutage/10.3.179.
5
Contribution of nitropyrene to the mutagenic activity of coal fly ash.硝基芘对粉煤灰致突变活性的贡献。
Environ Mutagen. 1984;6(2):131-44. doi: 10.1002/em.2860060204.
6
Mutagenic activity of the 4,5- and 9,10-dihydrodiols of benzo[j]fluoranthene and their syn- and anti-dihydrodiol epoxides in Salmonella typhimurium.苯并[j]荧蒽的4,5-和9,10-二氢二醇及其顺式和反式二氢二醇环氧化物在鼠伤寒沙门氏菌中的致突变活性。
Environ Mol Mutagen. 1993;22(1):34-45. doi: 10.1002/em.2850220107.
7
Tricyclic drugs: potent mutagenicity of traces of a nitroarene formed in the reaction of opipramol with nitrite.三环类药物：奥匹哌醇与亚硝酸盐反应中形成的痕量硝基芳烃具有强大的致突变性。
Mutat Res. 1987 Jan;190(1):7-11. doi: 10.1016/0165-7992(87)90074-1.
8
Formation of mutagens in boiled pork extract.水煮猪肉提取物中诱变剂的形成。
Food Chem Toxicol. 1982 Oct;20(5):531-3. doi: 10.1016/s0278-6915(82)80060-4.
9
Mutagenic and antimutagenic activities of aqueous and methanol extracts of Euphorbia hirta.飞扬草的水提物和甲醇提取物的致突变和抗致突变活性。
J Ethnopharmacol. 2009 Dec 10;126(3):406-14. doi: 10.1016/j.jep.2009.09.025. Epub 2009 Sep 22.
10
Mutagens in surface waters: a review.地表水中的诱变剂：综述
Mutat Res. 2004 Nov;567(2-3):109-49. doi: 10.1016/j.mrrev.2004.08.003.

本文引用的文献

1
Nitrate and nitrite: origin in humans.
Science. 1979 Sep 28;205(4413):1335-7. doi: 10.1126/science.205.4413.1335.
2
Endogenous synthesis of volatile nitrosamines: model calculations and risk assessment.
IARC Sci Publ. 1982(41):379-96.
3
A cautionary note the use of nitroreductase-deficient strains of Salmonella typhimurium for the detection of nitroarenes as mutagens in complex mixtures including diesel exhausts.一则警示：使用鼠伤寒沙门氏菌的硝基还原酶缺陷菌株来检测包括柴油机废气在内的复杂混合物中的硝基芳烃作为诱变剂。
Mutat Res. 1981 Mar;91(2):103-5. doi: 10.1016/0165-7992(81)90080-4.
4
Adsorption of mutagens to cotton bearing covalently bound trisulfo-copper-phthalocyanine.诱变剂在共价结合三磺基铜酞菁的棉花上的吸附作用。
Mutat Res. 1983 Mar;119(3):233-8. doi: 10.1016/0165-7992(83)90166-5.
5
Presence of 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid, a precursor of a mutagenic nitroso compound, in soy sauce.酱油中存在1-甲基-1,2,3,4-四氢-β-咔啉-3-羧酸，一种诱变亚硝基化合物的前体。
Proc Natl Acad Sci U S A. 1983 May;80(10):2912-6. doi: 10.1073/pnas.80.10.2912.
6
N-nitroso compounds: occurrence, biological effects and relevance to human cancer. Proceedings of the VIIIth International Symposium on N-Nitroso Compounds. Banff, Canada, 5-9 September 1983.N-亚硝基化合物：存在情况、生物学效应及其与人类癌症的关联。第八届国际N-亚硝基化合物研讨会会议论文集。1983年9月5日至9日于加拿大班夫
IARC Sci Publ. 1984(57):1-1011.
7
The basis of the insensitivity of Salmonella typhimurium strain TA98/1,8-DNP6 to the mutagenic action of nitroarenes.鼠伤寒沙门氏菌TA98/1,8 - DNP6菌株对硝基芳烃诱变作用不敏感的基础。
Mutat Res. 1983 Jul;121(1):17-23. doi: 10.1016/0165-7992(83)90081-7.
8
The nitrosation of alcohol-induced metabolites produces mutagenic substances.酒精诱导的代谢产物的亚硝化作用会产生诱变物质。
Mutat Res. 1985 Dec;158(3):159-68. doi: 10.1016/0165-1218(85)90079-5.
9
Appearance of direct-acting mutagenicity of various foodstuffs produced in Japan and Southeast Asia on nitrite treatment.
Mutat Res. 1985 Dec;158(3):119-24. doi: 10.1016/0165-1218(85)90073-4.
10
A mutagen precursor in Chinese cabbage, indole-3-acetonitrile, which becomes mutagenic on nitrite treatment.大白菜中的一种诱变前体，吲哚 - 3 - 乙腈，经亚硝酸盐处理后会变成诱变剂。
Mutat Res. 1985 May-Jun;143(1-2):17-21. doi: 10.1016/0165-7992(85)90098-3.

用亚硝酸处理后的米饭产生的致突变性。

Mutagenicity arising from boiled rice on treatment with nitrous acid.

作者信息

Hayatsu H, Hayatsu T

机构信息

Faculty of Pharmaceutical Sciences, Okayama University.

出版信息

Jpn J Cancer Res. 1989 Nov;80(11):1021-3. doi: 10.1111/j.1349-7006.1989.tb02252.x.

DOI:10.1111/j.1349-7006.1989.tb02252.x
PMID:2514162
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5917898/
Abstract

When an aqueous homogenate of boiled rice was treated with nitrous acid at pH 3, direct-acting mutagens were formed. The presence of the mutagens was demonstrated by isolating the mutagenic fractions through blue-rayon adsorption, a method used to extract polycyclic compounds, and subsequent high-performance liquid chromatography (HPLC). The mutagens were active in Salmonella typhimurium TA100 and TA98 without metabolic activation. Several different mutagens were formed, as judged from the HPLC profile.

摘要

当将煮熟大米的水匀浆在pH 3条件下用亚硝酸处理时，会形成直接作用的诱变剂。通过蓝光吸附（一种用于提取多环化合物的方法）分离诱变级分，随后进行高效液相色谱法（HPLC），证明了诱变剂的存在。这些诱变剂在鼠伤寒沙门氏菌TA100和TA98中具有活性，无需代谢活化。从HPLC图谱判断，形成了几种不同的诱变剂。