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Ethanol-induced genotoxicity.

作者信息

Hayes S

出版信息

Mutat Res. 1985 May-Jun;143(1-2):23-7. doi: 10.1016/0165-7992(85)90099-5.

DOI:10.1016/0165-7992(85)90099-5
PMID:3889601
Abstract

Unrelated, nondenatured, ethanol preparations, derived synthetically or by fermentation, were found to induce qualitatively similar concentration-dependent toxic and genotoxic effects as measured by RK mutatest. In this system ethanol was found genotoxic above a threshold concentration of 18-19% (v/v) when RK+ selector cells were transiently exposed for 10 min before selection for RK- survivors at 42 degrees C.

摘要

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