检测杂酚油和煤焦油中的挥发性诱变剂。

Detection of volatile mutagens in creosote and coal tar.

作者信息

Bos R P, Jongeneelen F J, Theuws J L, Henderson P T

出版信息

Mutat Res. 1985 Jun;156(3):195-8. doi: 10.1016/0165-1218(85)90064-3.

DOI:10.1016/0165-1218(85)90064-3

Abstract

Creosote and coal tar were examined for the presence of volatile mutagens by use of the so-called "taped plate assay". Application of this method, recently published by Distlerath et al., reveals that vapour escaping from creosote and coal tar at 37 degrees C was able to revert the Salmonella typhimurium strains TA98 and TA100 in the presence of S9 mix. The simplicity of this method makes it useful for routine screening of industrial fluids or solid products for the presence of volatile mutagens.

摘要

通过使用所谓的“胶带平板试验”检测了杂酚油和煤焦油中挥发性诱变剂的存在情况。Distlerath等人最近发表的这种方法的应用表明，在37摄氏度下从杂酚油和煤焦油中逸出的蒸汽能够在S9混合物存在的情况下使鼠伤寒沙门氏菌菌株TA98和TA100发生回复突变。这种方法的简单性使其可用于常规筛选工业流体或固体产品中挥发性诱变剂的存在情况。

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