关于治疗黄褐斑的新方法和现有治疗方法的最新进展。
An Update on New and Existing Treatments for the Management of Melasma.
机构信息
Department of Dermatology, St Vincent's Hospital, Melbourne, VIC, Australia.
Department of Dermatology, The Royal Children's Hospital, Melbourne, VIC, Australia.
出版信息
Am J Clin Dermatol. 2024 Sep;25(5):717-733. doi: 10.1007/s40257-024-00863-2. Epub 2024 Jun 19.
Abstract
Melasma is a chronic, acquired disorder of focal hypermelanosis that carries significant psychosocial impact and is challenging for both the patient and the treating practitioner to manage in the medium to long term. Multiple treatments have been explored, often in combination given the many aetiological factors involved in its pathogenesis. Therapeutic discoveries to treat melasma are a focal topic in the literature and include a range of modalities, with recent developments including updates on visible light photoprotection, non-hydroquinone depigmenting agents, oral tranexamic acid, chemical peels, and laser and energy-based device therapy for melasma. It is increasingly important yet challenging to remain up-to-date on the arsenal of treatments available for melasma to find an efficacious and well-tolerated option for our patients.
摘要
黄褐斑是一种慢性获得性局灶性色素沉着过度疾病，对患者和治疗医生都具有重要的心理社会影响，在中、长期管理上具有挑战性。已经探索了多种治疗方法，鉴于其发病机制涉及许多病因因素，通常会联合应用这些方法。治疗黄褐斑的治疗发现是文献中的一个重点研究课题，包括一系列治疗方法，最近的进展包括可见光光保护、非氢醌脱色剂、口服氨甲环酸、化学换肤以及用于治疗黄褐斑的激光和能量设备治疗的更新。了解治疗黄褐斑的现有治疗方法对于为我们的患者找到有效且耐受良好的治疗方案非常重要，但也极具挑战性。
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