Moji Branch Shinmoji Quarantine Facility, Animal Quarantine Service, MAFF, Fukuoka, Japan.
Microbiological Examination Division, Laboratory Department, Animal Quarantine Service, MAFF, Kanagawa, Japan.
J Vet Med Sci. 2024 Aug 2;86(8):828-832. doi: 10.1292/jvms.23-0342. Epub 2024 Jun 18.
Strangles is a globally widespread, commonly diagnosed and important infectious disease of equids caused by Streptococcus equi subsp. equi. We performed whole genome sequencing of 19 S. equi isolates collected from imported horses at the Japanese border. Of these isolates, 15 isolates were obtained from clinical cases and 4 were from subclinical cases. The 19 isolates were grouped into 3 Bayesian analysis of population structure (BAPS) groups by the core genome single nucleotide polymorphism analysis corresponding to exporting country, SeM typing, or exporter of the horses. The 19 isolates possessed same pathogenic genes regardless of clinical status in imported horses and no antimicrobial resistance genes. The disease status of the horses may rather reflect the prior exposure of animals with sub-clinical infection to S. equi.
马腺疫是一种在全球广泛传播、常见且重要的马属动物传染病，由马链球菌兽亚种引起。我们对从日本边境进口马匹中采集的 19 株马链球菌进行了全基因组测序。这些分离株中，15 株来自临床病例，4 株来自亚临床病例。根据核心基因组单核苷酸多态性分析，将 19 株分离株分为 3 个贝叶斯种群结构分析（BAPS）组，对应于出口国、SeM 分型或马匹出口商。19 株分离株具有相同的致病基因，无论进口马匹的临床状态如何，都没有抗菌药物耐药基因。马的疾病状态可能更能反映亚临床感染动物对马链球菌的先前暴露情况。
