Link M P
Pediatr Clin North Am. 1985 Jun;32(3):699-720.
The childhood non-Hodgkin's lymphomas (NHL) are histologically, immunologically, and clinically a heterogeneous group of diseases. Recent advances in our understanding of NHL have demonstrated the similarities between childhood NHL and childhood acute lymphoblastic leukemia (ALL). Treatment strategies utilizing systemic chemotherapy and modeled after successful treatment programs for ALL have resulted in a dramatic improvement in prognosis for children with NHL, and the majority of affected children are now curable.
儿童非霍奇金淋巴瘤(NHL)在组织学、免疫学和临床上是一组异质性疾病。我们对NHL认识的最新进展表明,儿童NHL与儿童急性淋巴细胞白血病(ALL)之间存在相似之处。采用全身化疗并以ALL成功治疗方案为蓝本的治疗策略,已使NHL患儿的预后得到显著改善,现在大多数患病儿童都可治愈。