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上唇多形性腺瘤(混合瘤):一例报告。

Pleomorphic adenoma (mixed tumor) of the upper lip: A case report.

作者信息

Chidzonga Midion Mapfumo, Mahomva Leonard, Zambuko Blessing, Muungani Welcome

机构信息

Department of Oral Health, University of Zimbabwe Faculty of Medicine and Health Sciences and Lancet Laboratory, Harare, Zimbabwe.

出版信息

World J Clin Cases. 2024 Jun 16;12(17):3138-3143. doi: 10.12998/wjcc.v12.i17.3138.

Abstract

BACKGROUND

Salivary gland tumors are relatively rare. Most minor salivary gland tumors are malignant with benign tumors accounting for 18% of the tumors. Pleomorphic adenoma (PA) is the most common salivary gland tumor. Lip PA is uncommon with 9.8% occurring in the upper lip. We are adding on the knowledge of the rare upper lip PA (benign mixed tumor).

CASE SUMMARY

We report an upper lip PA (benign mixed tumor) in a 28-year-old man. His complaint was a painless swelling on the upper lip. A painless, non-tender, well-circumscribed, slightly mobile, sessile, nodular, and rubbery (in consistency) tumor measuring 5.0 cm x 2.0 cm was noted on the left side of his upper lip. The overlying skin was not fixed and of normal color. There was no ulceration, and palpation did not elicit pain or bleeding. There was no history of trauma. Blunt dissection was used to completely excise the nodular, whitish, and encapsulated tumor. Microscopy showed a well-circumscribed and partly encapsulated biphasic lesion, with large lobules of myxo-chondroid stroma and intervening cellular nodules of basaloid cells, well-formed tubules containing eosinic secretion, and nests of myoepithelial cells. A diagnosis of PA (benign mixed tumor) was confirmed.

CONCLUSION

Blunt dissection is indicated to preserve the cosmesis and function of the upper lip.

摘要

背景

涎腺肿瘤相对罕见。大多数小涎腺肿瘤是恶性的,良性肿瘤占肿瘤的18%。多形性腺瘤(PA)是最常见的涎腺肿瘤。唇部PA不常见,9.8%发生在上唇。我们正在增加对罕见的上唇PA(良性混合瘤)的认识。

病例摘要

我们报告了一名28岁男性的上唇PA(良性混合瘤)。他的主诉是上唇无痛性肿胀。在上唇左侧发现一个无痛、无压痛、边界清楚、稍可移动、基底较宽、结节状且质地橡皮样(质地)的肿瘤,大小为5.0厘米×2.0厘米。覆盖其上的皮肤未固定且颜色正常。没有溃疡,触诊未引起疼痛或出血。无外伤史。采用钝性分离法完整切除了结节状、白色、有包膜的肿瘤。显微镜检查显示为边界清楚、部分有包膜的双相性病变,有大片黏液软骨样间质及其间的基底样细胞巢、含有嗜酸性分泌物的完好小管和肌上皮细胞巢。确诊为PA(良性混合瘤)。

结论

钝性分离法有助于保留上唇的美观和功能。

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