Almeslet Asma S
Department of Oral Maxillofacial Surgery and Diagnostic Sciences, Riyadh Elm University, Riyadh, Kingdom of Saudi Arabia.
Int J Clin Pediatr Dent. 2020 May-Jun;13(3):284-287. doi: 10.5005/jp-journals-10005-1776.
Pleomorphic adenoma (PA) is a commonly occurring benign tumor originating in the salivary glands.
The aim was to carry out a systematic literature of reports on pleomorphic adenoma from 2000 to 2018 to determine patient's age spread, gender, anatomical location, capsular invasion, histopathology, treatment and patient outcome.
A PubMed search was conducted with the following key words: adenoma, pleomorphic adenoma, and mixed salivary tumor.
Twenty-two articles in English were read in full after fulfilling the eligibility criteria. The mean age of PA occurrence was 44.14 years with a definite female predilection (M:F ratio = 13:8). It most commonly occurred in the facial region (42.85%), and surgical approach is the preferred intervention.
Pleomorphic adenomas are benign salivary gland neoplasms that can grow into extensive sizes if left untreated and hence need to be diagnosed early. Complete excision of the tumor is the definitive treatment, as enucleation can result in recurrence. Facial nerve has to be preserved if PA occurs in the parotid gland.
Almeslet AS. Pleomorphic Adenoma: A Systematic Review. Int J Clin Pediatr Dent 2020;13(3):284-287.
多形性腺瘤（PA）是一种常见的起源于唾液腺的良性肿瘤。
旨在对2000年至2018年有关多形性腺瘤的报告进行系统文献综述，以确定患者的年龄分布、性别、解剖位置、包膜侵犯、组织病理学、治疗方法及患者预后。
在PubMed上使用以下关键词进行检索：腺瘤、多形性腺瘤、涎腺混合瘤。
22篇符合入选标准的英文文章被全文阅读。多形性腺瘤发病的平均年龄为44.14岁，女性明显居多（男：女比例为13:8）。最常见于面部区域（42.85%），手术是首选的干预措施。
多形性腺瘤是良性唾液腺肿瘤，如果不治疗会发展到很大的体积，因此需要早期诊断。肿瘤的完整切除是确定性治疗方法，因为剜除术可能导致复发。如果多形性腺瘤发生在腮腺，必须保留面神经。
Almeslet AS.多形性腺瘤：系统评价。《国际临床儿科牙科学杂志》2020；13(3):284 - 287。
