Makkiyah Feda Anisah, Rahmi Eldiza Puji, Arista Rini Anggi, Marliani Nelly, Nurcholis Waras
Department of Neurosurgery, Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, West Java, Indonesia.
Department of Biochemistry, IPB University, Bogor, West Java, Indonesia.
J Adv Pharm Technol Res. 2024 Apr-Jun;15(2):111-116. doi: 10.4103/japtr.japtr_325_23. Epub 2024 May 6.
The antioxidant potential of (wungu leaves), an indigenous shrub plant extensively used in traditional medicine in Indonesia, was investigated in this study. The research focused on a comprehensive evaluation of total phenolic content (TPC), total flavonoid content (TFC), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and ferric-reducing antioxidant power (FRAP) across various plant parts, including roots, stems, and flowers, which had been underexplored in prior studies. The ethanol extract derived from wungu flowers and leaves demonstrated notable antioxidant potential, characterized by elevated TPC (12.22 ± 0.31 mg GAE/g DW) and FRAP (37.73 ± 1.08 μmol TEAC/g DW) in the ethanol extract of wungu flowers. Similarly, the ethanol extract of wungu leaves showcased a substantial TFC (2.31 ± 0.18 mg QE/g DW) and DPPH (1.12 ± 0.05 μmol TEAC/g DW), surpassing other parts of the wungu plant in the same or different extracts. These findings suggested that ethanol extracts were a promising foundation for herbal medicines with antioxidant properties, highlighting their potential applications in plant breeding programs. Furthermore, the correlation data underscored the significance of the ethyl acetate and ethanol extracts, revealing a robust correlation between TPC, TFC, and FRAP compared to the -hexane extract.
本研究对印度尼西亚传统医学中广泛使用的本土灌木植物(翁古叶)的抗氧化潜力进行了调查。该研究重点全面评估了总酚含量(TPC)、总黄酮含量(TFC)、2,2-二苯基-1-苦基肼(DPPH)以及铁还原抗氧化能力(FRAP),涉及根、茎和花等此前研究较少涉及的植物各部分。翁古花和叶的乙醇提取物显示出显著的抗氧化潜力,翁古花乙醇提取物中的TPC(12.22±0.31毫克没食子酸当量/克干重)和FRAP(37.73±1.08微摩尔TEAC/克干重)升高即为特征体现。同样,翁古叶乙醇提取物展现出较高的TFC(2.31±0.18毫克槲皮素当量/克干重)和DPPH(1.12±0.05微摩尔TEAC/克干重),在相同或不同提取物中超过翁古植物的其他部分。这些发现表明,乙醇提取物是具有抗氧化特性草药的一个有前景的基础,突出了它们在植物育种计划中的潜在应用。此外,相关数据强调了乙酸乙酯和乙醇提取物的重要性,揭示了与正己烷提取物相比,TPC、TFC和FRAP之间存在强相关性。