血流限制型抗阻训练对 2 型糖尿病老年患者代谢紊乱和身体成分的影响：一项随机对照研究。
Effect of blood flow-restrictive resistance training on metabolic disorder and body composition in older adults with type 2 diabetes: a randomized controlled study.
机构信息
School of Nursing, Shaoyang University, Shaoyang, Hunan, China.
Department of Endocrinology, The Second Affiliated Hospital of Shaoyang University, Shaoyang, Hunan, China.
出版信息
Front Endocrinol (Lausanne). 2024 Jun 6;15:1409267. doi: 10.3389/fendo.2024.1409267. eCollection 2024.
INTRODUCTION
To explore whether blood flow-restrictive resistance exercise (BFRE) can be used as an alternative strategy to moderate-intensity resistance training (RT) to improve metabolic disorder and body composition in older adults with type 2 diabetes (T2DM).
METHODS
This is a single-blind, randomized, controlled trial. Ninety-eight older adults with T2DM were randomly divided into three groups: BFRE group (n = 34), RT group (n = 31) and control group (n = 33). Two exercise groups received supervised collective training for a period of six months, each lasting 50 min, three times a week. The primary outcomes included fasting plasma glucose (FPG), Glycosylated hemoglobin (HbA1c), blood lipids, blood pressure, and body composition. The secondary outcome was muscle performance.
RESULTS
After six months of intervention, the FPG, HbA1c, blood lipids, diastolic blood pressure, body composition, and muscle performance of the two exercise groups were significantly improved relative to the control group and baseline measurements (P < 0.05). There was no significant increase in lean mass between the two exercise groups compared to the control group and baseline (p > 0.05). There was no significant decrease in systolic blood pressure between the two exercise groups compared to the control group (p > 0.05), but it was significantly lower than their baseline (P < 0.05). There was no significant difference in all indicators between the two exercise groups at the baseline, third and sixth months of intervention (p > 0.05).
DISCUSSION
BFRE can safely and effectively improve the metabolic disorder and body composition of older adults with T2DM. For elderly exercise beginners, BFRE can be used as an alternative strategy to moderate-intensity resistance training.
CLINICAL TRIAL REGISTRATION
https://www.chictr.org.cn/showproj.html?proj=178886, identifier ChiCTR2300074357.
简介
本研究旨在探讨血流限制型抗阻运动（BFRE）是否可作为一种替代中等强度抗阻训练（RT）的策略，改善 2 型糖尿病（T2DM）老年患者的代谢紊乱和身体成分。
方法
这是一项单盲、随机、对照试验。98 例 T2DM 老年患者被随机分为三组：BFRE 组（n = 34）、RT 组（n = 31）和对照组（n = 33）。两组运动组接受为期 6 个月的监督集体训练，每次 50 分钟，每周 3 次。主要结局包括空腹血糖（FPG）、糖化血红蛋白（HbA1c）、血脂、血压和身体成分。次要结局为肌肉性能。
结果
干预 6 个月后，与对照组和基线相比，两组运动组的 FPG、HbA1c、血脂、舒张压、身体成分和肌肉性能均显著改善（P < 0.05）。与对照组和基线相比，两组运动组的瘦体重均无显著增加（p > 0.05）。与对照组相比，两组运动组的收缩压无显著降低（p > 0.05），但与基线相比显著降低（P < 0.05）。两组运动组在基线、第 3 个月和第 6 个月的干预期间，所有指标均无显著差异（p > 0.05）。
讨论
BFRE 可安全有效地改善 T2DM 老年患者的代谢紊乱和身体成分。对于老年运动初学者，BFRE 可作为中等强度抗阻训练的替代策略。
临床试验注册
https://www.chictr.org.cn/showproj.html?proj=178886，标识符 ChiCTR2300074357。
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