Green D W, Sinclair J R, Mikhael M S
Anaesthesia. 1985 Apr;40(4):371-5. doi: 10.1111/j.1365-2044.1985.tb10793.x.
A randomised double-blind trial comparing morphine and buprenorphine and postoperative analgesia combined with droperidol was conducted in 60 patients. Compared with morphine, taken as the standard analgesic, buprenorphine was shown to be a satisfactory analgesic for major surgery, with no difference in the incidence of unwanted effects.
对60例患者进行了一项随机双盲试验,比较吗啡、丁丙诺啡及术后镇痛联合氟哌利多的效果。与作为标准镇痛药的吗啡相比,丁丙诺啡对大手术而言是一种令人满意的镇痛药,不良反应发生率无差异。