Diagnostic Imaging, Fox Chase Cancer Center, Philadelphia, Pennsylvania
J Nucl Med. 2024 Aug 1;65(8):1173-1174. doi: 10.2967/jnumed.124.267868.
The linear no-threshold (LNT) model, which asserts that any level of ionizing radiation increases cancer risk, has been the basis of global radiation protection policies since the 1950s. Despite ongoing endorsements, a growing body of evidence challenges the LNT model, suggesting instead that low-level radiation exposure might reduce cancer risk, a concept known as radiation hormesis. This editorial examines the persistence of the LNT model despite evidence favoring radiation hormesis and proposes a solution: a public, online debate between proponents of the LNT model and advocates of radiation hormesis. This debate, organized by a government agency like Medicare, would be transparent and thorough, potentially leading to a shift in radiation protection policies. Acceptance of radiation hormesis could significantly reduce cancer mortality rates and streamline radiation safety regulations, fostering medical innovation and economic growth.
线性无阈(LNT)模型认为,任何水平的电离辐射都会增加癌症风险,自 20 世纪 50 年代以来一直是全球辐射防护政策的基础。尽管仍在持续认可,但越来越多的证据对 LNT 模型提出了挑战,反而表明低水平的辐射暴露可能会降低癌症风险,这一概念被称为辐射兴奋效应。本社论探讨了尽管有证据支持辐射兴奋效应,但 LNT 模型仍在持续存在的问题,并提出了一个解决方案:在一个像医疗保险这样的政府机构的组织下,在 LNT 模型的支持者和辐射兴奋效应的倡导者之间进行公开的、在线的辩论。这场辩论将是透明和彻底的,可能会导致辐射防护政策的转变。接受辐射兴奋效应可以显著降低癌症死亡率,并简化辐射安全法规,促进医学创新和经济增长。