Department of Nursing, The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou, Zhejiang, People's Republic of China.
Oncologist. 2024 Oct 3;29(10):e1237-e1245. doi: 10.1093/oncolo/oyae141.
Although the overall incidence and mortality of colorectal cancer have declined, diagnosed cases of young-onset colorectal cancer have increased significantly. Concerns about future fertility are second only to concerns about survival and may significantly affect the quality of life of young cancer survivors. Fertility preservation is an important issue in young-onset colorectal patients with cancer undergoing oncotherapy. Here, we discussed the effects of different treatments on fertility, common options for fertility preservation, factors affecting fertility preservation and improvement measures, and the relationship between fertility and pregnancy outcomes in young-onset colorectal patients with cancer.
虽然结直肠癌的总体发病率和死亡率有所下降,但青年发病型结直肠癌的确诊病例显著增加。对未来生育能力的担忧仅次于对生存的担忧,可能会显著影响年轻癌症幸存者的生活质量。生育力保存是接受肿瘤治疗的青年发病型结直肠癌患者的一个重要问题。在这里,我们讨论了不同治疗方法对生育能力的影响、生育力保存的常见选择、影响生育力保存的因素和改进措施,以及青年发病型结直肠癌患者生育力与妊娠结局的关系。