从未接种和接种麻风分枝杆菌的犰狳器官中分离出的可培养分枝杆菌。

Cultivable mycobacteria isolated from organs of armadillos uninoculated and inoculated with Mycobacterium leprae.

作者信息

Portaels F, De Ridder K, Pattyn S R

出版信息

Ann Inst Pasteur Microbiol (1985). 1985 Mar-Apr;136A(2):181-90. doi: 10.1016/s0769-2609(85)80057-0.

Abstract

Mycobacteria were cultivated from 16 out of 32 samples of tissues from armadillos inoculated with Mycobacterium leprae. Three out of 7 samples from non-inoculated armadillos held in captivity were also positive for cultivable mycobacteria. Some isolated strains belonged to the M. avium-intracellulare-scrofulaceum complex, while others were identified as M. gordonae and M. terrae. Unclassified mycobacteria were isolated from M. leprae-inoculated armadillos only. Taxonomic studies confirmed that these new armadillo-derived mycobacteria (ADM) are different from all presently known species of mycobacteria, including M. leprae. The same new species were isolated from different armadillo colonies and were never found in non-inoculated animals. Different factors influence the isolation of these ADM in primary culture. Analysis of some specific markers of these ADM has been suggested in order to quantitatively determine the proportion of these ADM to M. leprae in armadillo tissues. No mycobacteria were cultivated from Nude mouse footpads infected with M. leprae.

摘要

从接种了麻风分枝杆菌的犰狳的32份组织样本中，有16份培养出了分枝杆菌。在圈养的未接种犰狳的7份样本中，有3份也能培养出分枝杆菌呈阳性。一些分离菌株属于鸟分枝杆菌-胞内分枝杆菌-瘰疬分枝杆菌复合体，而其他的则被鉴定为戈登分枝杆菌和地分枝杆菌。未分类的分枝杆菌仅从接种了麻风分枝杆菌的犰狳中分离出来。分类学研究证实，这些新的源自犰狳的分枝杆菌（ADM）与目前已知的所有分枝杆菌物种都不同，包括麻风分枝杆菌。相同的新物种从不同的犰狳群体中分离出来，从未在未接种的动物中发现。不同因素影响这些ADM在原代培养中的分离。有人建议分析这些ADM的一些特定标志物，以便定量确定犰狳组织中这些ADM与麻风分枝杆菌的比例。从感染了麻风分枝杆菌的裸鼠脚垫中未培养出分枝杆菌。