Stranne Johan, Hugosson Jonas, Lodding Pär
Department of Urology, Sahlgrenska University Hospital, Göteborg, Sweden.
J Urol. 2006 Nov;176(5):2072-6. doi: 10.1016/j.juro.2006.07.007.
Inguinal hernia after radical retropubic prostatectomy has been reported to occur in 7% to 21% of patients. We analyzed the impact of simultaneous pelvic lymph node dissection, preoperative inguinal hernia morbidity, postoperative anastomotic stricture, duration of surgery and patient age. We also compared the detection rate of inguinal hernia events in a retrospective patient file survey to that in a prospective patient administered questionnaire.
A total of 498 patients underwent radical retropubic prostatectomy plus pelvic lymph node dissection and 166 underwent radical retropubic prostatectomy only. Mean followup was 40 months (median 37, range 3 to 85). All 664 patients were analyzed in the patient file survey. The patient administered questionnaire was mailed preoperatively, and after 3, 6, 12, 18, 24 and 36 months to 271 patients who underwent operation between 2001 and 2002. A total of 207 patients (76.4%) completed the preoperative questionnaire.
The cumulative incidence of inguinal hernia after 24 months was 11.6% in the patient file survey and 15.7% in the patient administered questionnaire. In the patient file survey patient age was the only studied factor that significantly influenced risk. The patient file survey failed to detect half of the men with preoperative inguinal hernia morbidity and a third of post-radical retropubic prostatectomy inguinal hernias compared to the patient administered questionnaire. On patient administered questionnaire analysis preoperative inguinal hernia morbidity was a significant risk factor for postoperative inguinal hernia (log rank Mantel-Cox test p = 0.010).
Previous inguinal hernia morbidity and age increase the risk of post-radical retropubic prostatectomy inguinal hernia. Simultaneous pelvic lymph node dissection, postoperative anastomotic stricture and duration of surgery were not significant risk factors in this study. The patient file survey is inferior to the patient administered questionnaire for detecting inguinal hernia events.
据报道,耻骨后根治性前列腺切除术后腹股沟疝的发生率在7%至21%之间。我们分析了同时进行盆腔淋巴结清扫、术前腹股沟疝发病率、术后吻合口狭窄、手术时间和患者年龄的影响。我们还比较了回顾性患者档案调查和前瞻性患者问卷调查中腹股沟疝事件的检出率。
共有498例患者接受了耻骨后根治性前列腺切除术加盆腔淋巴结清扫,166例仅接受了耻骨后根治性前列腺切除术。平均随访时间为40个月(中位数37个月,范围3至85个月)。在患者档案调查中对所有664例患者进行了分析。患者问卷调查在术前以及术后3、6、12、18、24和36个月寄给2001年至2002年间接受手术的271例患者。共有207例患者(76.4%)完成了术前问卷。
在患者档案调查中,24个月后腹股沟疝的累积发生率为11.6%,在患者问卷调查中为15.7%。在患者档案调查中,患者年龄是唯一显著影响风险的研究因素。与患者问卷调查相比,患者档案调查未能检测出一半术前有腹股沟疝发病的男性以及三分之一耻骨后根治性前列腺切除术后腹股沟疝患者。根据患者问卷调查分析,术前腹股沟疝发病率是术后腹股沟疝的一个显著危险因素(对数秩Mantel-Cox检验p = 0.010)。
既往腹股沟疝发病率和年龄增加了耻骨后根治性前列腺切除术后腹股沟疝的风险。在本研究中,同时进行盆腔淋巴结清扫、术后吻合口狭窄和手术时间不是显著的危险因素。在检测腹股沟疝事件方面,患者档案调查不如患者问卷调查。