Brookmeyer R, Self S G
Biometrics. 1985 Mar;41(1):129-36.
A method called partial completion is proposed for predicting the gain in precision of the Kaplan-Meier survival curve associated with additional follow-up and accrual. This is accomplished by using the initial data to predict the numbers of patients who would be at risk at the observed death times by the end of the proposed second follow-up period. A consistency result ensures that the predictors will be accurate in large samples while simulation results suggest that the predictors are accurate with moderate sample sizes. The procedures are applied to a bone marrow transplant study and the Channing House data set.
提出了一种称为部分完成的方法,用于预测与额外随访和病例积累相关的Kaplan-Meier生存曲线精度的提高。这是通过使用初始数据来预测在提议的第二个随访期结束时在观察到的死亡时间处于风险中的患者数量来实现的。一个一致性结果确保预测器在大样本中是准确的,而模拟结果表明预测器在中等样本量时也是准确的。这些程序应用于一项骨髓移植研究和钱宁之家数据集。