Spooner R L, Millar P, Oliver R A
Anim Blood Groups Biochem Genet. 1979;10(2):99-105. doi: 10.1111/j.1365-2052.1979.tb01012.x.
This paper presents evidence to show that high titre antilymphocyte sera can be prepared more easily by skin grafting than from parous sera. It also shows that it is possible to analyse complex antilymphocyte sera by absorption with lymphocytes to produce working reagents. Following the 1 International BoLA Workshop the genotype of some of the animals used for skin grafting was ascertained and it was found that in each case where the resulting serum had been studied the main antiserum specificity that had been produced reacted with one of the BoLA specificities present in the skin donor.
本文提供的证据表明,通过皮肤移植比从经产血清更容易制备高滴度抗淋巴细胞血清。它还表明,通过用淋巴细胞吸收来分析复杂的抗淋巴细胞血清以制备工作试剂是可行的。在第一次国际组织相容性白细胞抗原(BoLA)研讨会后,确定了一些用于皮肤移植的动物的基因型,并且发现在每一个所研究的产生血清的案例中,所产生的主要抗血清特异性都与皮肤供体中存在的一种BoLA特异性发生反应。