Grad Simona, Vulturar Romana, Fărcaş Radu A, Dumitraşcu Dan L
Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Second Medical Department, Emergency County Clinical Hospital, Cluj-Napoca, Romania.
Med Pharm Rep. 2021 Nov;94(Suppl No 3):S38-S42. doi: 10.15386/mpr-2517. Epub 2021 Nov 29.
Non-alcoholic fatty liver disease (NAFLD) is characterized by an accumulation of hepatic fat, diagnosed histologically or radiologically (ultrasound), in the absence of a secondary cause of steatosis, especially alcohol consumption. Its prevalence is estimated to be approximately 25%. This high prevalence is correlated with the risk factors attributed to the metabolic syndrome. Non-alcoholic steatohepatitis (NASH) is a progressive form of NAFL and it can lead to end-stage liver disease in some patients. Once diagnosed, lifestyle changes must be initiated to lower hepatic fat accumulations in the liver. Physical exercise and diet play the most important role in achieving the desired weight loss goal.
非酒精性脂肪性肝病（NAFLD）的特征是肝脏脂肪堆积，通过组织学或放射学（超声）诊断，且不存在脂肪变性的继发原因，尤其是饮酒。据估计其患病率约为25%。这种高患病率与代谢综合征的危险因素相关。非酒精性脂肪性肝炎（NASH）是NAFL的一种进展形式，在某些患者中可导致终末期肝病。一旦确诊，必须开始改变生活方式以减少肝脏中的脂肪堆积。体育锻炼和饮食在实现理想的体重减轻目标方面起着最重要的作用。
