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40 岁以上患者行髋臼周围截骨术治疗髋关节发育不良:系统评价。

Hip Dysplasia Treated With Periacetabular Osteotomy in Patients Over 40 Years Old: A Systematic Review.

机构信息

Department of Orthopedic Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.

Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.

出版信息

Iowa Orthop J. 2024;44(1):105-112.

Abstract

BACKGROUND

Hip dysplasia is a leading cause of hip osteoarthritis. While periacetabular osteotomy (PAO) is effective for relieving pain and dysfunction caused by hip dysplasia in adolescents and young adults, there is concern that patients over 40 years of age will have an increased risk of persistent dysfunction and need for total hip arthroplasty. Current available evidence for PAO in older adults is limited and there is no systematic review in the literature focusing on this topic. The current systematic review offers insight into the demographics, patient-reported outcome measure (PROM) scores, and hip survivorship from total hip arthroplasty in patients over 40 years older treated for hip dysplasia with PAO.

METHODS

The review was conducted under the guidelines for the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA). Databases that were searched included PubMed, OVID Medline, SCOPUS, Embase, Cochrane Library, and clinicaltrials.gov. Studies were screened based on predetermined inclusion and exclusion criteria.

RESULTS

Five studies were included in this systematic review. Enrollment years were 1990-2013. In total, there were 335 hips with mean ages between 43.5-47.2 years. Mean follow up was 4-10.8 years. Most patients that underwent hip preservation had Tonnis osteoarthritis grade 0-1. There was contradicting evidence whether patients >40 years did better or worse compared to <40 years; although, most patients in the >40 years group had good outcomes after PAO. PAO survivorship ranged from 67-100% depending on the study. Complications ranged from 2-36% of cases depending on the study; although, none of these complications had lasting effects.

CONCLUSION

Patients over 40 years old appear to have positive outcomes when treated for hip dysplasia with PAO, though these patients were likely selected for no to minimal osteoarthritis, high functional status, and good health. PAO should be considered for patients with hip dysplasia over 40 years old without hip arthritis, though we recommend very selective indications. .

摘要

背景

髋关节发育不良是髋关节骨关节炎的主要原因。虽然髋臼周围截骨术(PAO)对于缓解青少年和年轻成人髋关节发育不良引起的疼痛和功能障碍是有效的,但人们担心 40 岁以上的患者会增加持续功能障碍和需要全髋关节置换的风险。目前针对老年人 PAO 的可用证据有限,文献中也没有专门针对这一主题的系统评价。本系统评价提供了关于接受 PAO 治疗髋关节发育不良的 40 岁以上患者的人口统计学、患者报告的结果测量(PROM)评分和全髋关节置换术后髋关节存活率的信息。

方法

本综述根据系统评价和荟萃分析的首选报告项目(PRISMA)指南进行。检索的数据库包括 PubMed、OVID Medline、SCOPUS、Embase、Cochrane 图书馆和 clinicaltrials.gov。根据预先确定的纳入和排除标准筛选研究。

结果

本系统评价纳入了 5 项研究。纳入研究的年份为 1990 年至 2013 年。共有 335 髋,平均年龄在 43.5-47.2 岁之间。平均随访时间为 4-10.8 年。大多数接受髋关节保护的患者的 Tonnis 骨关节炎分级为 0-1 级。关于 40 岁以上患者与 40 岁以下患者相比表现更好或更差,存在相互矛盾的证据;尽管如此,大多数>40 岁的患者在接受 PAO 后结果良好。PAO 的存活率因研究而异,范围为 67-100%。并发症的发生率因研究而异,范围为 2-36%;尽管这些并发症都没有产生持久的影响。

结论

对于接受髋臼周围截骨术治疗髋关节发育不良的 40 岁以上患者,似乎有积极的结果,但这些患者可能是由于没有或仅有轻度骨关节炎、高功能状态和良好的健康状况而被选择。对于 40 岁以上无髋关节关节炎的髋关节发育不良患者,应考虑行 PAO,但我们建议非常有选择性地使用该方法。

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Developmental Dysplasia of the Hip in Adolescents and Young Adults.青少年和青年的髋关节发育不良。
J Am Acad Orthop Surg. 2020 Feb 1;28(3):91-101. doi: 10.5435/JAAOS-D-18-00533.

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