Mittwoch U
J Med Genet. 1985 Jun;22(3):164-70. doi: 10.1136/jmg.22.3.164.
Throughout the major part of history, theories of sex determination had to be formulated in the absence of knowledge of ova and spermatozoa. The most persistent theory postulated that males are associated with the right parental side and females with the left side. At the end of the 19th century, sex was thought to be determined by nutrition. Recent findings regarding bilateral asymmetry in human hermaphrodites and of temperature dependent sex determination in reptiles may restore a small degree of credibility to certain theories predating the discovery of sex chromosomes.
在历史的大部分时期，性别的决定理论是在人们对卵子和精子缺乏了解的情况下形成的。最持久的理论假定，男性与父系的右侧相关，女性与左侧相关。在19世纪末，人们认为性别是由营养决定的。关于人类雌雄同体者双侧不对称以及爬行动物温度依赖性性别决定的最新发现，可能会让某些在性染色体发现之前的理论恢复一定程度的可信度。
