Kariya Chihiro, Kanzaki Hiroyuki, Kumazawa Masao, Sahara Saaya, Yoshida Kana, Inagawa Yuri, Kobayashi Fumitaka, Tomonari Hiroshi
Department of Orthodontics, School of Dental Medicine, Tsurumi University, Yokohama 230-8501, Japan.
Dent J (Basel). 2024 May 27;12(6):161. doi: 10.3390/dj12060161.
The masticatory function of patients with skeletal anterior open bite (OPEN) is reported to be impaired compared with that of patients with normal occlusion (NORM). In this study, we compared brain blood flow (BBF) in patients with OPEN and NORM and investigated the factors related to BBF during mastication in patients with OPEN. The study included 17 individuals with NORM and 33 patients with OPEN. The following data were collected: number of occlusal contacts, jaw movement variables during mastication, and BBF measured with functional near-infrared spectroscopy during chewing. The number of occlusal contacts, maximum closing and opening speeds, closing angle, and vertical amplitude were smaller in the OPEN than in the NORM group. Interestingly, BBF increased less in the OPEN group. Correlation analysis revealed that several parameters, including number of occlusal contacts and closing angle, were correlated with changes in BBF during mastication. These results suggest that not only occlusion but also jaw movement variables and factors related to masticatory muscles contribute to the chewing-related increase in BBF. In conclusion, BBF increases less during mastication in patients with OPEN than in those with NORM. In addition, the higher increase in BBF is correlated with jaw movement. Together, we discovered that OPEN exhibits significant adverse effects not only on masticatory function but also on brain function.
据报道，与正常咬合（NORM）患者相比，骨骼性前牙开颌（OPEN）患者的咀嚼功能受损。在本研究中，我们比较了OPEN患者和NORM患者的脑血流量（BBF），并研究了OPEN患者咀嚼过程中与BBF相关的因素。该研究纳入了17名NORM个体和33名OPEN患者。收集了以下数据：咬合接触次数、咀嚼过程中的颌骨运动变量，以及咀嚼过程中用功能近红外光谱测量的BBF。OPEN组的咬合接触次数、最大闭口和开口速度、闭口角度和垂直幅度均低于NORM组。有趣的是，OPEN组的BBF增加较少。相关性分析显示，包括咬合接触次数和闭口角度在内的几个参数与咀嚼过程中BBF的变化相关。这些结果表明，不仅咬合，而且颌骨运动变量和与咀嚼肌相关的因素都有助于咀嚼相关的BBF增加。总之，OPEN患者咀嚼过程中BBF的增加低于NORM患者。此外，BBF的较高增加与颌骨运动相关。我们共同发现，OPEN不仅对咀嚼功能，而且对脑功能都有显著的不良影响。
