Numan Ahmad Mousa, Halim Haddad Fares
Department of Nutrition and Food Technology, Human Nutrition and Dietetics, The University of Jordan, Amman11942..
Endocrinology Division, Department of Internal Medicine, King Hussein Medical Center, Amman, Jordan..
Nutr Hosp. 2015 Dec 1;32(6):2701-9. doi: 10.3305/nh.2015.32.6.9543.
visceral adiposity index (VAI) has recently been proposed as a predictor of cardiometabolic risk, but its usefulness has not been confirmed.
to evaluate the association between VAI and conventional adiposity and cardiometabolic risk indices and examine VAI risk predictive ability and compare it with other adiposity indices.
a total of 1 622 Jordanian adults, 686 men and 936 women, aged 20-80 years were included this study. VAI, body mass index (BMI), waist circumference (WC), waist-hip ratio (WHR), waist-height ratio (WHtR) were examined and high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), fasting serum glucose (FSG), systolic (SBP), and diastolic (DBP) blood pressure were determined. Associations and age-and gender specific distribution and differences were evaluated. Receiver operating characteristic (ROC) curve and area under curve (AUC) were used for risk predictive ability comparison.
VAI of women (6.82±6.43) was higher than of men (4.15±4.62). VAI severity increased with age in a dose-response trend (p<0.001) in both genders. Women had higher prevalence than men of high risks of VAI and all adiposity and cardiometabolic indices. VAI markedly associated with TG, HDL-C, FSG, SBP and DBP or WHR, WC, WHtR and BMI in respective order of correlation potency for cardiometabolic or adiposity risk indices. In men and women respectively, the largest AUC was for VAI (0.79 vs. 0.77), followed by WHR (0.73 vs. 0.75), WC (0.69 vs. 0.74), WHtR (0.65 vs. 0.71) and BMI (0.53 vs. 0.51).
the findings suggest that VAI potentially associates with cardiometabolic risks and proves to be superior to other adiposity indices in predicting such risk.
内脏脂肪指数(VAI)最近被提出作为心脏代谢风险的预测指标,但其有效性尚未得到证实。
评估VAI与传统肥胖及心脏代谢风险指标之间的关联,检验VAI的风险预测能力,并将其与其他肥胖指标进行比较。
本研究纳入了1622名年龄在20至80岁之间的约旦成年人,其中男性686名,女性936名。检测了VAI、体重指数(BMI)、腰围(WC)、腰臀比(WHR)、腰高比(WHtR),并测定了高密度脂蛋白胆固醇(HDL-C)、甘油三酯(TG)、空腹血糖(FSG)、收缩压(SBP)和舒张压(DBP)。评估了相关性以及年龄和性别特异性分布与差异。采用受试者工作特征(ROC)曲线和曲线下面积(AUC)进行风险预测能力比较。
女性的VAI(6.82±6.43)高于男性(4.15±4.62)。在男女两性中,VAI严重程度均随年龄呈剂量反应趋势增加(p<0.001)。女性VAI及所有肥胖和心脏代谢指标高风险的患病率均高于男性。VAI与TG、HDL-C、FSG、SBP和DBP或WHR、WC、WHtR和BMI显著相关,在心脏代谢或肥胖风险指标方面的相关强度依次排列。在男性和女性中,AUC最大的分别是VAI(0.79对0.77),其次是WHR(0.73对0.75)、WC(0.69对0.74)、WHtR(0.65对0.71)和BMI(0.53对0.51)。
研究结果表明,VAI可能与心脏代谢风险相关,并且在预测此类风险方面优于其他肥胖指标。