Filonov A E, Rublevskaia A E, Boronin A M
Mikrobiologiia. 1985 Mar-Apr;54(2):227-32.
The stability of the conjugative plasmid RP4 and the nonconjugative plasmid pBS94 in Escherichia coli C600 cells containing both plasmids was studied in continuous cultivation under chemostat and pH-stat conditions. The plasmids remained stable in the cells of the bacterial population for 100 generations, and no cells were found without the plasmids. The competition between strains with and without the plasmids in a mixed culture resulted in the removal of the plasmid-free strain from the population. In these experiments, conjugative transfer of plasmids into the plasmid-free strain was observed, and co-transfer of both plasmids was more effective under the pH-stat conditions.
在恒化器和pH稳定条件下的连续培养中，研究了接合质粒RP4和非接合质粒pBS94在同时含有这两种质粒的大肠杆菌C600细胞中的稳定性。这些质粒在细菌群体的细胞中保持稳定达100代，未发现无质粒的细胞。在混合培养中，有质粒和无质粒菌株之间的竞争导致无质粒菌株从群体中被清除。在这些实验中，观察到质粒向无质粒菌株的接合转移，并且在pH稳定条件下两种质粒的共转移更有效。
