Dragomir Ramona Elena, Toader Daniela Oana, Gheoca Mutu Daniela Elena, Dogaru Iulian Alexandru, Răducu Laura, Tomescu Laurențiu Cezar, Moleriu Lavinia Cristina, Bordianu Anca, Petre Ion, Stănculescu Ruxandra
Doctoral School, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Department of Obstetrics and Gynecology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Life (Basel). 2024 May 31;14(6):714. doi: 10.3390/life14060714.
Maternal-fetal gestational pathology is one of the biggest challenges in the field of health at this moment. The current study is designed to determine the effects of vitamin D on pregnancy, starting with the idea that impairment of vitamin D status is thought to be correlated with impairment of the newborn's health.
In this retrospective study, we tried to establish the link between vitamin D deficiency and maternal characteristics and also how it impacted the clinical status of the newborn. We analyzed a group of 260 patients: 130 pregnant women and 130 newborns, in whom vitamin D status was detected using the serum levels of 25-hydroxyvitamin D (25-(OH)D).
The results showed that vitamin D deficiency has a high incidence among pregnant women, as was presented in many important international studies. Our study also showed a positive, direct correlation between the mother's and newborn's vitamin D status.
Taking into consideration that vitamin D deficiency has been correlated with many complications, both in maternal and newborn health, a serum level determination of 25-(OH)D is necessary in the first trimester of pregnancy, and after that, adequate supplementation is necessary in order to prevent any negative effects.
母婴妊娠病理是当前健康领域面临的最大挑战之一。本研究旨在确定维生素D对妊娠的影响,研究起始于维生素D状态受损被认为与新生儿健康受损相关这一观点。
在这项回顾性研究中,我们试图建立维生素D缺乏与母亲特征之间的联系,以及它如何影响新生儿的临床状况。我们分析了一组260名患者:130名孕妇和130名新生儿,通过检测血清25-羟基维生素D(25-(OH)D)水平来确定其维生素D状态。
结果表明,维生素D缺乏在孕妇中发病率很高,正如许多重要国际研究中所呈现的那样。我们的研究还表明,母亲和新生儿的维生素D状态之间存在正相关、直接的关联。
鉴于维生素D缺乏与母婴健康方面的许多并发症相关,在妊娠早期有必要测定血清25-(OH)D水平,在此之后,为预防任何负面影响,进行充分补充是必要的。