Agatston A S, Chengot M, Rao A, Hildner F, Samet P
Am J Cardiol. 1985 Jul 1;56(1):106-9. doi: 10.1016/0002-9149(85)90575-2.
Twenty-five consecutive elderly patients with suspected aortic stenosis underwent continuous-wave Doppler echocardiography followed by cardiac catheterization. Doppler-derived calculations of peak and mean aortic valve gradients were compared with catheterization-derived values of peak-to-peak, peak and mean gradients. The best correlation was found between Doppler- and catheterization-derived mean gradients (r = 0.89). A Doppler-derived measure of the timing of peak aortic flow velocity (modified time-to-peak velocity/modified left ventricular ejection time) successfully separated those with gradients above or below 50 mm Hg and also helped to avoid over- or underestimation of aortic valve gradients by Doppler.
连续25例疑似主动脉瓣狭窄的老年患者接受了连续波多普勒超声心动图检查，随后进行了心导管检查。将多普勒得出的主动脉瓣峰值和平均梯度计算值与心导管检查得出的峰-峰、峰值和平均梯度值进行比较。发现多普勒得出的平均梯度与心导管检查得出的平均梯度之间相关性最佳（r = 0.89）。一种由多普勒得出的主动脉峰值流速时间测量方法（改良的峰值流速时间/改良的左心室射血时间）成功区分了梯度高于或低于50 mmHg的患者，还有助于避免多普勒对主动脉瓣梯度的高估或低估。
