Kiełtyka-Dadasiewicz Anna, Esteban Javier, Jabłońska-Trypuć Agata
Department of Plant Production Technology and Commodities Science, University of Life Sciences in Lublin, 20-950 Lublin, Poland.
Garden of Cosmetic Plants and Raw Materials, Research and Science Innovation Centre, 20-819 Lublin, Poland.
Pharmaceuticals (Basel). 2024 May 29;17(6):705. doi: 10.3390/ph17060705.
The importance of natural plant materials in modern medicine is considerable, and raw materials with antiviral, antibacterial, antifungal, and anticancer properties are still sought because of microbe resistance and difficulties in anticancer therapy. This review focuses on the lemongrass (DC.) Stapf. and on the lemongrass oil properties and applications. Multiple applications of this plant were described in different latitudes and cultures, including cases of digestive disorders and anti-inflammatory, antipyretic, diaphoretic, stimulating, and antispasmodic conditions. Data from the literature on the composition of essential oil and extracts from were analyzed, and the results of research on the antifungal, antibacterial, and antiviral effects were quoted. Essential oil inhibits the growth of fungi (, , spp.) and has an antibacterial effect (, , ). It also shows antiviral activity and deters insects. Lemongrass contains active substances with potential anticancer effects. This plant has apoptosis-stimulating properties, mainly through the activity of apigenin, which is the main active flavonoid in this plant. This active substance helps inhibit cell proliferation by stopping the cell cycle and directing cancer cells toward apoptosis.
天然植物材料在现代医学中具有重要意义，由于微生物耐药性和抗癌治疗的困难，仍在寻找具有抗病毒、抗菌、抗真菌和抗癌特性的原材料。本综述聚焦于柠檬草（(DC.) Stapf.）及其精油的特性和应用。这种植物在不同纬度和文化中有多种应用，包括消化系统疾病以及抗炎、解热、发汗、刺激和解痉等情况。分析了关于柠檬草精油和提取物成分的文献数据，并引用了其抗真菌、抗菌和抗病毒作用的研究结果。精油可抑制真菌（、、 spp.）生长并具有抗菌作用（、、）。它还具有抗病毒活性并能驱虫。柠檬草含有具有潜在抗癌作用的活性物质。这种植物具有刺激细胞凋亡的特性，主要通过芹菜素的活性来实现，芹菜素是该植物中的主要活性黄酮类化合物。这种活性物质通过阻止细胞周期并引导癌细胞凋亡来帮助抑制细胞增殖。
