无临床肾脏异常的系统性红斑狼疮：肾活检结果及临床病程
Systemic lupus erythematosus without clinical renal abnormalities: renal biopsy findings and clinical course.
作者信息
O'Dell J R, Hays R C, Guggenheim S J, Steigerwald J C
出版信息
Ann Rheum Dis. 1985 Jun;44(6):415-9. doi: 10.1136/ard.44.6.415.
Abstract
The extent and significance of renal biopsy abnormalities in patients with systemic lupus erythematosus (SLE) without clinical renal abnormalities is controversial. We report 11 consecutive SLE patients who were biopsied without clinical renal abnormalities. All 11 patients had mesangial changes either by light microscopy or by immunofluorescent staining, and none had changes of focal or diffuse proliferative glomerulonephritis. Additionally none had deterioration of renal function during the mean follow-up period of 6.3 years.
摘要
系统性红斑狼疮（SLE）患者无临床肾脏异常时肾活检异常的程度及意义存在争议。我们报告了11例连续接受活检且无临床肾脏异常的SLE患者。11例患者通过光学显微镜或免疫荧光染色均有系膜改变，且均无局灶性或弥漫性增殖性肾小球肾炎改变。此外，在平均6.3年的随访期内，无一例患者出现肾功能恶化。
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