Yu Xi, Jia Yuanqiang, Ren Feiyue
School of Food and Health, Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Engineering, and Technology Research Center of Food Additives, Beijing Technology and Business University (BTBU), Beijing, China.
Front Nutr. 2024 Jun 12;11:1408651. doi: 10.3389/fnut.2024.1408651. eCollection 2024.
Resveratrol (RES) is a naturally occurring polyphenolic compound. Recent studies have identified multiple potential health benefits of RES, including antioxidant, anti-inflammatory, anti-obesity, anticancer, anti-diabetic, cardiovascular, and neuroprotective properties. The objective of this review is to summarize and analyze the studies on the biological activities of RES in disease prevention and treatment, as well as its metabolism and bioavailability. It also discusses the challenges in its clinical application and future research directions. RES exhibits significant potential in the prevention and treatment of many diseases. The future direction of RES research should focus on improving its bioavailability, conducting more clinical trials to determine its effectiveness in humans, and investigating its mechanism of action. Once these challenges have been overcome, RES is expected to become an effective health intervention.
白藜芦醇（RES）是一种天然存在的多酚化合物。最近的研究已经确定了RES的多种潜在健康益处，包括抗氧化、抗炎、抗肥胖、抗癌、抗糖尿病、心血管保护和神经保护特性。本综述的目的是总结和分析关于RES在疾病预防和治疗中的生物学活性及其代谢和生物利用度的研究。它还讨论了其临床应用中的挑战和未来的研究方向。RES在许多疾病的预防和治疗中具有显著潜力。RES研究的未来方向应集中在提高其生物利用度、进行更多临床试验以确定其对人类的有效性以及研究其作用机制上。一旦这些挑战得到克服，RES有望成为一种有效的健康干预措施。
