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在植入金黄仓鼠的皮下小室中培养梅毒螺旋体。

Cultivation of Treponema pallidum in subcutaneous chambers implanted in golden hamsters.

作者信息

Morrison G D, Egglestone S I, Northwood J L

出版信息

Br J Vener Dis. 1979 Oct;55(5):320-4. doi: 10.1136/sti.55.5.320.

DOI:10.1136/sti.55.5.320
PMID:389350
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1045671/
Abstract

Treponema pallidum was successfully grown in subcutaneous chambers in golden hamsters. Abnormally long forms of T. pallidum were found in these chambers. The cause of this abnormality may possibly be due to their being coated with antibody which could inhibit cell division or render the organism avirulent or both. T. pallidum was successfully passaged between hamsters but with a possible diminution in virulence.

摘要

梅毒螺旋体在金黄仓鼠的皮下小室中成功培养。在这些小室中发现了形态异常长的梅毒螺旋体。这种异常的原因可能是它们被抗体包裹，抗体可能会抑制细胞分裂或使病原体无毒或两者兼而有之。梅毒螺旋体在仓鼠之间成功传代，但毒力可能有所减弱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cca7/1045671/a814629d0094/brjvendis00035-0011-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cca7/1045671/50a21c907709/brjvendis00035-0009-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cca7/1045671/02aba2c15db1/brjvendis00035-0011-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cca7/1045671/a814629d0094/brjvendis00035-0011-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cca7/1045671/50a21c907709/brjvendis00035-0009-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cca7/1045671/02aba2c15db1/brjvendis00035-0011-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cca7/1045671/a814629d0094/brjvendis00035-0011-b.jpg

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Cultivation of Treponema pallidum in subcutaneous chambers implanted in golden hamsters.在植入金黄仓鼠的皮下小室中培养梅毒螺旋体。
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引用本文的文献

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J Clin Pathol. 1980 Aug;33(8):798. doi: 10.1136/jcp.33.8.798-a.

本文引用的文献

1
[Study of the effect of penicillin in late syphilis: persistence of Treponema pallidum following treatment. 1. Late syphilis--expeimental].[青霉素治疗晚期梅毒的效果研究：治疗后梅毒螺旋体的持续存在。1. 晚期梅毒——实验性研究]
Ann Inst Pasteur (Paris). 1962 May;102:596-615.
2
Neisseria gonorrhoeae: experimental infection of laboratory animals.淋病奈瑟菌：实验动物的感染实验
Science. 1972 Sep 29;177(4055):1200-1. doi: 10.1126/science.177.4055.1200.
3
Cultivation of pathogenic Treponema pallidum in chambers surgically implanted in experimental animals.
将致病性梅毒螺旋体接种于手术植入实验动物体内的小室中进行培养。
Acta Pathol Microbiol Scand B Microbiol Immunol. 1973 Apr;81(2):269-71. doi: 10.1111/j.1699-0463.1973.tb00223.x.
4
Treponema pallidum infection in subcutaneous polyethylene chambers in rabbits.兔皮下聚乙烯腔室中的梅毒螺旋体感染
Infect Immun. 1976 Jun;13(6):1606-12. doi: 10.1128/iai.13.6.1606-1612.1976.