• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

一项关于经皮外周神经刺激治疗慢性疼痛的前瞻性研究综述。

A review of prospective studies regarding percutaneous peripheral nerve stimulation treatment in the management of chronic pain.

机构信息

Department of Anesthesiology & Pain Medicine, University of California Davis Health, Sacramento, CA  95817, USA.

Department of Anesthesiology, Pain & Perioperative Medicine, University of Kansas Medical Center, Kansas City, KS  66103, USA.

出版信息

Pain Manag. 2024;14(4):209-222. doi: 10.1080/17581869.2024.2352398. Epub 2024 Jun 10.

DOI:10.1080/17581869.2024.2352398
PMID:38939963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11234914/
Abstract

Conventionally, peripheral nerve stimulation (PNS) for treatment of chronic pain has involved a two-stage process: a short-term (e.g., 7 days) trial and, if significant pain relief is achieved, a permanent PNS system is implanted. A percutaneous PNS treatment is now available where a coiled lead may be implanted for up to 60 days with the goal of producing sustained relief. In the present review, published prospective trials using percutaneous PNS treatment were identified and synthesized. The collected evidence indicates that percutaneous PNS treatment for up to 60 days provides durable clinically significant improvements in pain and pain interference. Similar efficacy across diverse targets and etiologies supports the broad applicability for use within the chronic pain population using this nonopioid technology.

摘要

传统上，外周神经刺激（PNS）治疗慢性疼痛包括两个阶段的过程：短期（例如，7 天）试验，如果疼痛得到显著缓解，则植入永久性 PNS 系统。现在可以进行经皮 PNS 治疗，其中可以植入螺旋形引线长达 60 天，目的是产生持续缓解。在本综述中，确定并综合了使用经皮 PNS 治疗的已发表前瞻性试验。收集到的证据表明，经皮 PNS 治疗长达 60 天可提供持久的临床显著的疼痛和疼痛干扰改善。针对不同的靶点和病因具有相似的疗效，支持在慢性疼痛人群中使用这种非阿片类技术广泛应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11234914/c38d82a379ff/IPMT_A_2352398_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11234914/59426bfc0464/IPMT_A_2352398_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11234914/09d81fd803cc/IPMT_A_2352398_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11234914/c38d82a379ff/IPMT_A_2352398_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11234914/59426bfc0464/IPMT_A_2352398_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11234914/09d81fd803cc/IPMT_A_2352398_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11234914/c38d82a379ff/IPMT_A_2352398_F0003_C.jpg

相似文献

1
A review of prospective studies regarding percutaneous peripheral nerve stimulation treatment in the management of chronic pain.一项关于经皮外周神经刺激治疗慢性疼痛的前瞻性研究综述。
Pain Manag. 2024;14(4):209-222. doi: 10.1080/17581869.2024.2352398. Epub 2024 Jun 10.
2
Percutaneous Peripheral Nerve Stimulation (PNS) for the Treatment of Chronic Low Back Pain Provides Sustained Relief.经皮外周神经刺激（PNS）治疗慢性腰痛可提供持续缓解。
Neuromodulation. 2019 Jul;22(5):615-620. doi: 10.1111/ner.12854. Epub 2018 Oct 3.
3
Percutaneous Peripheral Nerve Stimulation for Chronic Low Back Pain: Prospective Case Series With 1 Year of Sustained Relief Following Short-Term Implant.经皮外周神经刺激治疗慢性下腰痛：短期植入后 1 年持续缓解的前瞻性病例系列研究。
Pain Pract. 2020 Mar;20(3):310-320. doi: 10.1111/papr.12856. Epub 2019 Dec 2.
4
Percutaneous Peripheral Nerve Stimulation for the Treatment of Chronic Pain Following Amputation.经皮周围神经刺激治疗截肢后慢性疼痛
Mil Med. 2019 Jul 1;184(7-8):e267-e274. doi: 10.1093/milmed/usz114.
5
Real-world evidence of durable multi-dimensional improvement after 60-day peripheral nerve stimulation treatment used for shoulder pain.在使用外周神经刺激治疗 60 天后，真实世界证据显示肩痛的多维度持久改善。
Pain Manag. 2024;14(7):355-364. doi: 10.1080/17581869.2024.2371779. Epub 2024 Jul 23.
6
Percutaneous Peripheral Nerve Stimulation for Pain Reduction and Improvements in Functional Outcomes in Chronic Low Back Pain.经皮外周神经刺激用于慢性下腰痛的疼痛减轻及功能预后改善
Mil Med. 2019 Mar 1;184(Suppl 1):537-541. doi: 10.1093/milmed/usy310.
7
A Retrospective Review of Real-world Outcomes Following 60-day Peripheral Nerve Stimulation for the Treatment of Chronic Pain.60 天外周神经刺激治疗慢性疼痛的真实世界结局回顾性研究。
Pain Physician. 2023 May;26(3):273-281.
8
Treatment of chronic axial back pain with 60-day percutaneous medial branch PNS: Primary end point results from a prospective, multicenter study.采用 60 天经皮内侧支 PNS 治疗慢性轴向腰痛：前瞻性、多中心研究的主要终点结果。
Pain Pract. 2021 Nov;21(8):877-889. doi: 10.1111/papr.13055. Epub 2021 Jul 27.
9
Durable patient-reported outcomes following 60-day percutaneous peripheral nerve stimulation (PNS) of the medial branch nerves.内侧支神经60天经皮外周神经刺激（PNS）后的持久患者报告结局
Interv Pain Med. 2023 Mar 13;2(1):100243. doi: 10.1016/j.inpm.2023.100243. eCollection 2023 Mar.
10
Randomized Placebo-Controlled Trial of 60-Day Percutaneous Peripheral Nerve Stimulation Treatment Indicates Relief of Persistent Postoperative Pain, and Improved Function After Knee Replacement.随机安慰剂对照试验 60 天经皮外周神经刺激治疗表明缓解持续性术后疼痛，并改善膝关节置换术后功能。
Neuromodulation. 2024 Jul;27(5):847-861. doi: 10.1016/j.neurom.2024.03.001. Epub 2024 May 11.

引用本文的文献

1
Temporary Peripheral Nerve Stimulation (PNS) of the Cervical Medial Branch Nerve (CMBN) for Chronic Axial Neck Pain-A Literature Review and Case Series.用于慢性轴性颈部疼痛的颈内侧支神经临时周围神经刺激术——文献综述与病例系列
J Clin Med. 2025 Aug 21;14(16):5910. doi: 10.3390/jcm14165910.
2
Consensus Guidelines from the American Society of Pain and Neuroscience for the Use of 60-Day Peripheral Nerve Stimulation Therapy. A NEURON Living Guideline Project.美国疼痛与神经科学学会关于使用60天外周神经刺激疗法的共识指南。一个NEURON生活指南项目。
J Pain Res. 2025 Jun 24;18:3117-3139. doi: 10.2147/JPR.S521788. eCollection 2025.
3

本文引用的文献

1
A Retrospective Review of Real-world Outcomes Following 60-day Peripheral Nerve Stimulation for the Treatment of Chronic Pain.60 天外周神经刺激治疗慢性疼痛的真实世界结局回顾性研究。
Pain Physician. 2023 May;26(3):273-281.
2
Peripheral Nerve Stimulation for Low Back Pain: A Systematic Review.用于治疗腰痛的周围神经刺激：一项系统评价
Curr Pain Headache Rep. 2023 May;27(5):117-128. doi: 10.1007/s11916-023-01109-2. Epub 2023 Apr 15.
3
Chronic Pain Among Adults - United States, 2019-2021.成年人慢性疼痛 - 美国，2019-2021 年。
Durable Shoulder Pain Relief and Avoidance of Surgery Up To 5 Years Following 60-Day PNS Treatment.
60天周围神经刺激（PNS）治疗后长达5年的持久肩部疼痛缓解及避免手术
Pain Ther. 2025 May 26. doi: 10.1007/s40122-025-00746-2.
MMWR Morb Mortal Wkly Rep. 2023 Apr 14;72(15):379-385. doi: 10.15585/mmwr.mm7215a1.
4
Peripheral Nerve Stimulation for the Treatment of Postamputation Pain: A Systematic Review.外周神经刺激治疗截肢后疼痛：系统评价。
Am J Phys Med Rehabil. 2023 Sep 1;102(9):846-854. doi: 10.1097/PHM.0000000000002237. Epub 2023 Mar 11.
5
Implantable Peripheral Nerve Stimulation for Peripheral Neuropathic Pain: A Systematic Review of Prospective Studies.植入式周围神经刺激治疗周围神经病理性疼痛：前瞻性研究的系统评价
Biomedicines. 2022 Oct 17;10(10):2606. doi: 10.3390/biomedicines10102606.
6
Real-world evidence of sustained improvement following 60-day peripheral nerve stimulation treatment for pain: a cross-sectional follow-up survey.真实世界证据表明，外周神经刺激治疗疼痛 60 天后持续改善：一项横断面随访调查。
Pain Manag. 2022 Jul;12(5):611-621. doi: 10.2217/pmt-2022-0005. Epub 2022 May 5.
7
60-Day PNS Treatment May Improve Identification of Delayed Responders and Delayed Non-Responders to Neurostimulation for Pain Relief.60天的周围神经刺激（PNS）治疗可能会改善对神经刺激缓解疼痛的延迟反应者和延迟无反应者的识别。
J Pain Res. 2022 Mar 14;15:733-743. doi: 10.2147/JPR.S349101. eCollection 2022.
8
Incidence of Temporary Peripheral Nerve Stimulator Lead Tip Retention: A Retrospective Review of 80 Lead Placements.临时外周神经刺激器导联尖端留存的发生率：80次导联植入的回顾性研究
Neuromodulation. 2023 Apr;26(3):690-693. doi: 10.1016/j.neurom.2022.01.018. Epub 2022 Feb 26.
9
Gradation of Clinical Holistic Response as New Composite Outcome to Evaluate Success in Spinal Cord Stimulation Studies for Pain.将临床整体反应分级作为评估脊髓刺激治疗疼痛研究成功与否的新综合结局指标。
Neuromodulation. 2023 Jan;26(1):139-146. doi: 10.1016/j.neurom.2021.10.020. Epub 2021 Dec 18.
10
Peripheral Nerve Stimulation for Treatment of Headaches: An Evidence-Based Review.周围神经刺激治疗头痛：一项基于证据的综述。
Biomedicines. 2021 Oct 31;9(11):1588. doi: 10.3390/biomedicines9111588.