Institute for Cellular and Molecular Biology, The University of Texas, Austin, TX, 78712, USA; Department of Molecular Biosciences, The University of Texas, Austin, TX, 78712, USA.
Institute for Cellular and Molecular Biology, The University of Texas, Austin, TX, 78712, USA; Department of Molecular Biosciences, The University of Texas, Austin, TX, 78712, USA.
Curr Opin Plant Biol. 2024 Oct;81:102592. doi: 10.1016/j.pbi.2024.102592. Epub 2024 Jun 27.
Plant hormones activate receptors, initiating intracellular signaling pathways. Eventually, hormone-specific transcription factors become active in the nucleus, facilitating hormone-induced transcriptional regulation. Chromatin plays a fundamental role in the regulation of transcription, the process by which genetic information encoded in DNA is converted into RNA. The structure of chromatin, a complex of DNA and proteins, directly influences the accessibility of genes to the transcriptional machinery. The different signaling pathways and transcription factors involved in the transmission of information from the receptors to the nucleus have been readily explored, but not so much for the specific mechanisms employed by the cell to ultimately instruct the chromatin changes necessary for a fast and robust transcription activation, specifically for plant hormone responses. In this review, we will focus on the advancements in understanding how chromatin receives plant hormones, facilitating the changes necessary for fast, robust, and specific transcriptional regulation.
植物激素激活受体,启动细胞内信号通路。最终,激素特异性转录因子在核内变得活跃,促进激素诱导的转录调控。染色质在转录调控中起着至关重要的作用,转录是将 DNA 中编码的遗传信息转化为 RNA 的过程。染色质的结构,即 DNA 和蛋白质的复合物,直接影响基因对转录机制的可及性。受体到核内信息传递所涉及的不同信号通路和转录因子已经得到了充分的研究,但对于细胞最终指导染色质改变以实现快速、稳健和特异性转录激活所需的具体机制,特别是对于植物激素反应,研究还不够深入。在这篇综述中,我们将重点关注理解染色质如何接收植物激素的研究进展,以促进快速、稳健和特异性转录调控所需的变化。