Department of Orthopedics, Yan'an Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, 650051, P. R. China.
Osteoporos Int. 2024 Sep;35(9):1625-1631. doi: 10.1007/s00198-024-07164-8. Epub 2024 Jun 28.
Compared with the healthy patients, patients with osteoporosis had a lower Hounsfield unit (HU) value and a higher vertebral bone quality (VBQ) score. Both the HU value and VBQ score can simply distinguish patients with osteoporosis (OP), with a cutoff value of HU value < 97.06 and VBQ score > 3.08.
The purpose of this study is to determine whether the opportunistic use of computed tomography (CT) or magnetic resonance imaging (MRI) is effective for identifying spine surgical patients with OP.
We retrospectively evaluated 109 lumbar spine surgery patients who received lumbar quantitative CT (QCT) and MRI. Using the area under the curve, the CT-based HU value and MRI-based VBQ score were calculated. Then, based on the QCT results, receiver operating characteristic (ROC) curves were constructed to determine the diagnostic performance of the HU value and VBQ score.
The HU value was significantly lower in the OP group, and the VBQ score was significantly higher in the OP group. Using the area under the curve, the diagnostic performance of the HU value and VBQ score for OP were 0.959 and 0.880, respectively. The diagnostic threshold values determined with optimal sensitivity and specificity were an HU value of 97.06 and a VBQ score of 3.08.
Opportunistic use of CT and MRI can simply distinguish patients with OP, which are expected to be potential alternatives to T-score for the osteoporosis screening.
与健康患者相比，骨质疏松症患者的亨氏单位（HU）值较低，椎体骨质量（VBQ）评分较高。HU 值和 VBQ 评分都可以简单地区分骨质疏松症（OP）患者，截断值为 HU 值<97.06 和 VBQ 评分>3.08。
本研究旨在确定是否可以通过机会性使用计算机断层扫描（CT）或磁共振成像（MRI）来识别脊柱手术患者的 OP。
我们回顾性评估了 109 例接受腰椎定量 CT（QCT）和 MRI 的腰椎手术患者。使用曲线下面积，计算 CT 基于 HU 值和 MRI 基于 VBQ 评分。然后，根据 QCT 结果，构建接受者操作特征（ROC）曲线，以确定 HU 值和 VBQ 评分的诊断性能。
OP 组的 HU 值明显较低，OP 组的 VBQ 评分明显较高。使用曲线下面积，HU 值和 VBQ 评分对 OP 的诊断性能分别为 0.959 和 0.880。确定最佳敏感性和特异性的诊断阈值分别为 HU 值 97.06 和 VBQ 评分 3.08。
机会性使用 CT 和 MRI 可以简单地区分 OP 患者，有望成为骨质疏松症筛查的 T 评分替代方法。
