Centre for Preventive Neurology, Wolfson Institute of Population Health, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Portsmouth Hospital University Trust, Portsmouth, UK.
J Parkinsons Dis. 2024;14(5):993-997. doi: 10.3233/JPD-240005.
Reduced spontaneous blinking is a recognized Parkinson's disease (PD) feature. In contrast, voluntary blinking has been less studied and might serve as a measurable marker of facial bradykinesia. We tested 31 PD patients and 31 controls. Participants were filmed during conversation and a rapid blinking task. Both tasks were videorecorded to count the number of blinks per second. PD patients had lower blink rates. Rapid blinking accurately discriminated between groups with 77% sensitivity and 71% specificity. To conclude, rapid blinking may be a simple and quantifiable task of facial bradykinesia.
眨眼减少是公认的帕金森病(PD)特征。相比之下,自愿眨眼的研究较少,它可能是面部运动迟缓的可测量标志物。我们测试了 31 名 PD 患者和 31 名对照者。参与者在交谈和快速眨眼任务中被拍摄。两个任务都被录像,以计算每秒眨眼次数。PD 患者的眨眼频率较低。快速眨眼能以 77%的灵敏度和 71%的特异性准确区分两组。总之,快速眨眼可能是一种简单且可量化的面部运动迟缓的任务。