• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

中国成年人眨眼率对帕金森病诊断的有效性。

The validity of eye blink rate in Chinese adults for the diagnosis of Parkinson's disease.

作者信息

Chen W H, Chiang T J, Hsu M C, Liu J S

机构信息

Department of Neurology, Chang Gung Memorial Hospital, 123 Ta Pei Road, Niao Sung Hsiang, Kaohsiung 833, Taiwan, ROC.

出版信息

Clin Neurol Neurosurg. 2003 Apr;105(2):90-2. doi: 10.1016/s0303-8467(02)00107-5.

DOI:10.1016/s0303-8467(02)00107-5
PMID:12691797
Abstract

We evaluated the eye blink rate (EBR) in healthy Chinese adults and Parkinson's disease (PD) patients. In healthy subjects, the EBR declined with age, was lower in women than men younger than 50 years of age, and did not differ from male PD patients older than 60 years or female PD patients older than 50 years. Accordingly, EBR is not a good indicator for bradykinesia in Chinese individual older than 50 years that is prevalent for PD onset also.

摘要

我们评估了健康中国成年人和帕金森病(PD)患者的眨眼率(EBR)。在健康受试者中,EBR随年龄下降,50岁以下女性低于男性,且与60岁以上男性PD患者或50岁以上女性PD患者无差异。因此,对于50岁以上的中国个体而言,EBR不是运动迟缓的良好指标,而运动迟缓在PD发病中也很常见。

相似文献

1
The validity of eye blink rate in Chinese adults for the diagnosis of Parkinson's disease.中国成年人眨眼率对帕金森病诊断的有效性。
Clin Neurol Neurosurg. 2003 Apr;105(2):90-2. doi: 10.1016/s0303-8467(02)00107-5.
2
Rapid Voluntary Blinking as a Clinical Marker of Parkinson's Disease.快速自主眨眼作为帕金森病的临床标志物。
J Parkinsons Dis. 2024;14(5):993-997. doi: 10.3233/JPD-240005.
3
Using Spontaneous Eye-blink Rates to Predict the Motor Status of Patients with Parkinson's Disease.利用自发眨眼率预测帕金森病患者的运动状态。
Intern Med. 2019;58(10):1417-1421. doi: 10.2169/internalmedicine.1960-18. Epub 2019 May 15.
4
Symptom study in context: effects of marital quality on signs of Parkinson's disease during patient-spouse interaction.
Psychiatry. 1998 Spring;61(1):35-45. doi: 10.1080/00332747.1998.11024817.
5
Objective Assessment of Bradykinesia Estimated from the Wrist Extension in Older Adults and Patients with Parkinson's Disease.从老年人和帕金森病患者的手腕伸展评估运动徐缓。
Ann Biomed Eng. 2017 Nov;45(11):2614-2625. doi: 10.1007/s10439-017-1908-3. Epub 2017 Aug 29.
6
Measurement of spontaneous blinks in patients with Parkinson's disease using a new high-speed blink analysis system.使用新型高速眨眼分析系统测量帕金森病患者的自发性眨眼。
J Neurol Sci. 2017 Sep 15;380:200-204. doi: 10.1016/j.jns.2017.07.035. Epub 2017 Jul 29.
7
Facial bradykinesia.面部运动迟缓。
J Neurol Neurosurg Psychiatry. 2013 Jun;84(6):681-5. doi: 10.1136/jnnp-2012-303993. Epub 2012 Dec 12.
8
Quantification of whole-body bradykinesia in Parkinson's disease participants using multiple inertial sensors.使用多个惯性传感器对帕金森病患者的全身运动迟缓进行定量分析。
J Neurol Sci. 2018 Apr 15;387:157-165. doi: 10.1016/j.jns.2018.02.001. Epub 2018 Feb 2.
9
A little trouble getting started: Initial slowness in Parkinson's disease step negotiation.起步有点困难:帕金森病步态起步时的初始迟缓
Gait Posture. 2017 Sep;57:97-101. doi: 10.1016/j.gaitpost.2017.05.030. Epub 2017 May 31.
10
The Rolex sign: first manifestation of Parkinson's disease: case report.
Arq Neuropsiquiatr. 2000 Sep;58(3A):724-5. doi: 10.1590/s0004-282x2000000400020.

引用本文的文献

1
Spontaneous eye blink-based machine learning for tracking clinical fluctuations in Parkinson's disease.基于自发眨眼的机器学习用于追踪帕金森病的临床波动情况。
NPJ Parkinsons Dis. 2025 Aug 19;11(1):247. doi: 10.1038/s41531-025-01094-w.
2
Attentional modulation of eye blinking is altered by sex, age, and task structure.眨眼的注意力调节会因性别、年龄和任务结构而改变。
eNeuro. 2024 Feb 8;11(3). doi: 10.1523/ENEURO.0296-23.2024.
3
Wearable and Invisible Sensor Design for Eye-Motion Monitoring Based on Ferrofluid and Electromagnetic Sensing Technologies.
基于铁磁流体和电磁传感技术的用于眼动监测的可穿戴隐形传感器设计
Bioengineering (Basel). 2023 Apr 25;10(5):514. doi: 10.3390/bioengineering10050514.
4
Intra-subject consistency of spontaneous eye blink rate in young women across the menstrual cycle.年轻女性在月经周期内自发眨眼率的个体内一致性。
Sci Rep. 2020 Sep 24;10(1):15666. doi: 10.1038/s41598-020-72749-2.
5
Spontaneous eye blink rate and dopamine synthesis capacity: preliminary evidence for an absence of positive correlation.自发性眨眼率与多巴胺合成能力:缺乏正相关关系的初步证据。
Eur J Neurosci. 2018 May;47(9):1081-1086. doi: 10.1111/ejn.13895. Epub 2018 Mar 26.
6
Individual differences in eye blink rate predict both transient and tonic pupil responses during reversal learning.眨眼率的个体差异可预测逆向学习过程中的瞬态和紧张性瞳孔反应。
PLoS One. 2017 Sep 29;12(9):e0185665. doi: 10.1371/journal.pone.0185665. eCollection 2017.
7
Interactive Effects of Dopamine Baseline Levels and Cycle Phase on Executive Functions: The Role of Progesterone.多巴胺基线水平与月经周期阶段对执行功能的交互作用:孕酮的作用
Front Neurosci. 2017 Jul 13;11:403. doi: 10.3389/fnins.2017.00403. eCollection 2017.
8
Neurobiological correlates of impulsivity in healthy adults: Lower prefrontal gray matter volume and spontaneous eye-blink rate but greater resting-state functional connectivity in basal ganglia-thalamo-cortical circuitry.健康成年人冲动性的神经生物学相关性:较低的前额叶灰质体积和自发性眨眼率,但基底神经节-丘脑-皮质回路的静息状态功能连接更强。
Neuroimage. 2017 Aug 15;157:288-296. doi: 10.1016/j.neuroimage.2017.06.015. Epub 2017 Jun 8.
9
Effects of meditation practice on spontaneous eyeblink rate.冥想练习对自发眨眼率的影响。
Psychophysiology. 2016 May;53(5):749-58. doi: 10.1111/psyp.12619. Epub 2016 Feb 12.
10
Case-control study of blink rate in Parkinson's disease under different conditions.帕金森病不同状态下眨眼频率的病例对照研究。
J Neurol. 2012 Apr;259(4):739-44. doi: 10.1007/s00415-011-6261-0. Epub 2011 Oct 8.