Kirshenbaum J M, Lorell B H, Schoen F J, Bettmann M A, Thompson G B
J Am Coll Cardiol. 1985 Aug;6(2):486-9. doi: 10.1016/s0735-1097(85)80191-1.
A 33 year old woman with chronic myelogenous leukemia presented with clinical symptoms and hemodynamic signs suggestive of pulmonary embolism. Initial angiographic studies supported the diagnosis of a massive saddle pulmonary embolus, and an inferior vena cava filter was inserted. However, subsequent autopsy revealed unsuspected angioinvasive pulmonary aspergillosis with secondary in situ thrombosis. The clinical features and diagnostic considerations in immunocompromised patients presenting with the clinical picture of pulmonary embolism are discussed.
一名33岁的慢性粒细胞白血病女性患者出现了提示肺栓塞的临床症状和血流动力学体征。最初的血管造影研究支持了巨大鞍状肺栓塞的诊断,并植入了下腔静脉滤器。然而,随后的尸检发现了未被怀疑的血管侵袭性肺曲霉病伴继发性原位血栓形成。本文讨论了免疫功能低下患者出现肺栓塞临床表现时的临床特征和诊断注意事项。