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瘤型麻风与感觉缺失足部的夏科关节病:一例报告

Lepromatous Leprosy and Charcot Neuroarthropathy of Insensate Feet: A Case Report.

作者信息

Kress Gavin T, Swerdlow Mark, Shin Laura

机构信息

Vascular Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, USA.

出版信息

Cureus. 2024 May 30;16(5):e61362. doi: 10.7759/cureus.61362. eCollection 2024 May.

DOI:10.7759/cureus.61362
PMID:38947585
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11214381/
Abstract

Leprosy is a chronic infection of the skin, eyes, and peripheral nerves due to the slow-growing, acid-fast bacillus . Devastating complications include Charcot neuroarthropathy and insensate hands and feet. We present the case of an 81-year-old female with rheumatoid arthritis and 50 years of polar lepromatous leprosy who suffered from bilateral collapsed arches, flat feet, and bone deformities of Charcot feet.

摘要

麻风病是一种由生长缓慢的抗酸杆菌引起的皮肤、眼睛和周围神经的慢性感染。严重的并发症包括夏科氏关节病以及手足感觉丧失。我们报告一例81岁女性患者,她患有类风湿关节炎,患瘤型麻风50年,出现双侧足弓塌陷、扁平足和夏科氏足的骨骼畸形。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11214381/bedf1c13caef/cureus-0016-00000061362-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11214381/fded5ec29af5/cureus-0016-00000061362-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11214381/bedf1c13caef/cureus-0016-00000061362-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11214381/fded5ec29af5/cureus-0016-00000061362-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11214381/bedf1c13caef/cureus-0016-00000061362-i02.jpg

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Lepromatous Leprosy and Charcot Neuroarthropathy of Insensate Feet: A Case Report.瘤型麻风与感觉缺失足部的夏科关节病:一例报告
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本文引用的文献

1
An overview of Charcot's neuroarthropathy.夏科氏关节病概述。
J Clin Transl Endocrinol. 2020 Oct 28;22:100239. doi: 10.1016/j.jcte.2020.100239. eCollection 2020 Dec.
2
Myelin breakdown favours Mycobacterium leprae survival in Schwann cells.髓磷脂的破坏有利于麻风分枝杆菌在施万细胞中的存活。
Cell Microbiol. 2020 Jan;22(1):e13128. doi: 10.1111/cmi.13128. Epub 2019 Nov 13.
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Diabetic Foot Ulcers and Their Recurrence.糖尿病足溃疡及其复发
N Engl J Med. 2017 Jun 15;376(24):2367-2375. doi: 10.1056/NEJMra1615439.
4
Charcot Neuropathic Arthropathy of the Foot: A Literature Review and Single-Center Experience.足部夏科特神经病变性关节病:文献综述与单中心经验
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Downregulation of PHEX in multibacillary leprosy patients: observational cross-sectional study.多菌型麻风病患者中PHEX的下调:观察性横断面研究
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IL-17 cytokines in bone healing of diabetic Charcot arthropathy patients: a prospective 2 year follow-up study.白细胞介素-17细胞因子在糖尿病夏科氏关节病患者骨愈合中的作用:一项为期2年的前瞻性随访研究。
J Foot Ankle Res. 2015 Aug 18;8:39. doi: 10.1186/s13047-015-0096-3. eCollection 2015.
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Classifications in brief: Eichenholtz classification of Charcot arthropathy.简要分类:夏科特关节病的艾兴霍尔茨分类法。
Clin Orthop Relat Res. 2015 Mar;473(3):1168-71. doi: 10.1007/s11999-014-4059-y. Epub 2014 Nov 21.
8
Leprosy: review of the epidemiological, clinical, and etiopathogenic aspects - part 1.麻风病:流行病学、临床及病因学方面综述 - 第1部分
An Bras Dermatol. 2014 Mar-Apr;89(2):205-18. doi: 10.1590/abd1806-4841.20142450.
9
An overview of the Charcot foot pathophysiology.夏科氏足病生理机制概述。
Diabet Foot Ankle. 2013 Aug 2;4. doi: 10.3402/dfa.v4i0.21117. Print 2013.
10
The role of proinflammatory cytokines in the cause of neuropathic osteoarthropathy (acute Charcot foot) in diabetes.促炎细胞因子在糖尿病性神经性骨关节病(急性夏科氏足)病因中的作用。
Lancet. 2005 Dec 10;366(9502):2058-61. doi: 10.1016/S0140-6736(05)67029-8. Epub 2005 Aug 10.