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一例以急性冠状动脉综合征为表现的嗜铬细胞瘤病例。

A Case of Pheochromocytoma Presenting With Acute Coronary Syndrome.

作者信息

Dhadwad Jagannath S, Kadiwala Ramiz S, Kishore Sheetal N, Chitnis Anish, Sanghani Dhairya

机构信息

General Medicine, Dr. Dnyandeo Yashwantrao Patil Medical College, Hospital and Research Centre, Dr. Dnyandeo Yashwantrao Patil Vidyapeeth (Deemed to be University) Pune, Pune, IND.

出版信息

Cureus. 2024 May 30;16(5):e61389. doi: 10.7759/cureus.61389. eCollection 2024 May.

DOI:10.7759/cureus.61389
PMID:38947651
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11214641/
Abstract

Pheochromocytoma is a rare endocrine tumor originating from chromaffin cells of the adrenal medulla, which leads to the overproduction of catecholamines. Most symptoms, ranging from simple headaches to life-threatening cardiac arrests, are due to excess catecholamines. Usually, patients present with persistent or paroxysmal hypertension, headaches, sweating, and palpitations. Here, we describe a case that initially presented as an acute coronary syndrome and was treated accordingly. However, she had a history of nocturnal awakenings and panic attacks, which she had ignored for a month. On further evaluation, it turned out to be pheochromocytoma. This case report will surely help physicians better diagnose and treat such cases.

摘要

嗜铬细胞瘤是一种罕见的内分泌肿瘤,起源于肾上腺髓质的嗜铬细胞,可导致儿茶酚胺分泌过多。大多数症状,从简单的头痛到危及生命的心脏骤停,都是由儿茶酚胺过量引起的。通常,患者会出现持续性或阵发性高血压、头痛、出汗和心悸。在此,我们描述一例最初表现为急性冠状动脉综合征并接受相应治疗的病例。然而,她有夜间惊醒和惊恐发作的病史,她对此忽视了一个月。进一步评估后,发现是嗜铬细胞瘤。本病例报告肯定会帮助医生更好地诊断和治疗此类病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11df/11214641/c61c4ec032bf/cureus-0016-00000061389-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11df/11214641/155c6df83d4a/cureus-0016-00000061389-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11df/11214641/aac3b2e8be85/cureus-0016-00000061389-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11df/11214641/c61c4ec032bf/cureus-0016-00000061389-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11df/11214641/155c6df83d4a/cureus-0016-00000061389-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11df/11214641/aac3b2e8be85/cureus-0016-00000061389-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11df/11214641/c61c4ec032bf/cureus-0016-00000061389-i03.jpg

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A Case of Pheochromocytoma Presenting With Acute Coronary Syndrome.一例以急性冠状动脉综合征为表现的嗜铬细胞瘤病例。
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本文引用的文献

1
Pheochromocytoma Mimicking Acute Coronary Syndrome: A Case Report.嗜铬细胞瘤伪装成急性冠状动脉综合征:一例报告
Front Oncol. 2022 Apr 13;12:879714. doi: 10.3389/fonc.2022.879714. eCollection 2022.
2
Pheochromocytoma and Paraganglioma.嗜铬细胞瘤和副神经节瘤。
N Engl J Med. 2019 Aug 8;381(6):552-565. doi: 10.1056/NEJMra1806651.
3
Perioperative hemodynamics and outcomes of patients on metyrosine undergoing resection of pheochromocytoma or paraganglioma.接受嗜铬细胞瘤或副神经节瘤切除术的间变酪氨酸酶患者的围手术期血液动力学和结局。
Int J Surg. 2017 Oct;46:1-6. doi: 10.1016/j.ijsu.2017.08.026. Epub 2017 Aug 10.
4
[Acute coronary syndrome: a mode of uncommon revelation of pheochromocytoma].[急性冠状动脉综合征:嗜铬细胞瘤一种不常见的表现形式]
Pan Afr Med J. 2015 Oct 16;22:151. doi: 10.11604/pamj.2015.22.151.7505. eCollection 2015.
5
Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline.嗜铬细胞瘤和副神经节瘤:内分泌学会临床实践指南
J Clin Endocrinol Metab. 2014 Jun;99(6):1915-42. doi: 10.1210/jc.2014-1498.
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Clinical spectrum of pheochromocytoma.嗜铬细胞瘤的临床特征。
J Am Coll Surg. 2009 Dec;209(6):727-32. doi: 10.1016/j.jamcollsurg.2009.09.022.
7
Pheochromocytoma: current approaches and future directions.嗜铬细胞瘤:当前方法与未来方向。
Oncologist. 2008 Jul;13(7):779-93. doi: 10.1634/theoncologist.2008-0043. Epub 2008 Jul 10.
8
Comparison of CT findings in symptomatic and incidentally discovered pheochromocytomas.有症状和偶然发现的嗜铬细胞瘤的CT表现比较。
AJR Am J Roentgenol. 2005 Sep;185(3):684-8. doi: 10.2214/ajr.185.3.01850684.
9
Cardiovascular manifestations of pheochromocytoma.嗜铬细胞瘤的心血管表现。
Am J Emerg Med. 2000 Sep;18(5):622-5. doi: 10.1053/ajem.2000.7341.
10
Adrenal pheochromocytoma remains a frequently overlooked diagnosis.
Am J Surg. 2000 Mar;179(3):212-5. doi: 10.1016/s0002-9610(00)00296-8.