Qureshi Pir Abdul Ahad Aziz, Zeb Shah, Tryggvason Thordur, Þórisson Arnar
Department of Radiology, Landspítali - The National University Hospital of Iceland, Reykjavík, ISL.
Faculty of Medicine, Háskóli Íslands, Reykjavík, ISL.
Cureus. 2024 May 30;16(5):e61346. doi: 10.7759/cureus.61346. eCollection 2024 May.
Undifferentiated pleomorphic sarcoma (UPS), formerly known as malignant fibrous histiocytoma (MFH), constitutes a significant subset of soft-tissue sarcomas. Despite its rarity, UPS poses substantial clinical challenges due to its aggressive behavior and propensity for distant metastasis. Here, we report a rare case of high-grade UPS located in the colon, a site exceptionally uncommon for this malignancy, in a 49-year-old woman. The case also underscores the importance of considering UPS in the differential diagnosis of colonic neoplasms. Understanding the clinical and pathological features of UPS in unusual locations like the large intestine is crucial for timely diagnosis and appropriate management strategies.
未分化多形性肉瘤（UPS），以前称为恶性纤维组织细胞瘤（MFH），是软组织肉瘤的一个重要亚组。尽管UPS罕见，但由于其侵袭性和远处转移倾向，它带来了重大的临床挑战。在此，我们报告一例罕见的位于结肠的高级别UPS病例，该部位对于这种恶性肿瘤来说极为罕见，患者为一名49岁女性。该病例还强调了在结肠肿瘤的鉴别诊断中考虑UPS的重要性。了解像大肠这样不寻常部位的UPS的临床和病理特征对于及时诊断和采取适当的管理策略至关重要。
