Deihim Behnaz, Masoudipour Parisa
Infectious and Tropical Diseases Research Center, Dezful University of Medical Sciences, Dezful, Iran.
Department of Bacteriology and Virology, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran.
J Family Med Prim Care. 2024 May;13(5):2073-2077. doi: 10.4103/jfmpc.jfmpc_1594_23. Epub 2024 May 24.
Gastrointestinal infections affect many people annually. The most common bacterial agents involved in these infections are enteropathogenic bacteria and in the continuation of using broad-spectrum antibiotics, -associated diarrhea is involved, especially in hospitalized patients. The aim of the present study was to investigate the pattern of antibiotic resistance among enteropathogenic bacteria.
In this cross-sectional study, 163 samples of patients with diarrhea in Dezful Ganjavian Hospital were examined. The samples were cultured in MacConkey, Hektoen enteric agar and GN broth, and cycloserine cefoxitin fructose agar media and incubated under standard conditions. In order to identify enteropathogenic bacteria, biochemical tests and serological confirmatory tests were used. Antibiotic resistance pattern of the isolates was investigated by Kirby-Bauer disk diffusion susceptibility test.
The frequency of pathogenic bacteria includes 41.1% of , followed by 41.1% of , 6.7% of Enteropathogenic , 5.5% of Serogroup B, and 5.5% of . The results revealed a total of 46 patients with orders regarding culture, no was isolated from the samples. The studied isolates showed the highest resistance to trimethoprim-sulfamethoxazole, and ceftriaxone (88.3%), and the most effective antibiotic in the treatment of patients was ciprofloxacin with 86% sensitivity.
Susceptibility to antibiotics was different among the isolates, which shows that the early identification of the infection agent and the selection of the correct antibiotic treatment are effective in improving the gastrointestinal infection and preventing the spread of the infection.
胃肠道感染每年影响许多人。这些感染中最常见的细菌病原体是肠道致病菌，在持续使用广谱抗生素的情况下，会引发相关性腹泻，尤其是在住院患者中。本研究的目的是调查肠道致病菌的抗生素耐药模式。
在这项横断面研究中，对德兹富尔甘贾维安医院的163例腹泻患者样本进行了检查。样本在麦康凯、赫氏肠道琼脂和GN肉汤以及环丝氨酸头孢西丁果糖琼脂培养基中培养，并在标准条件下孵育。为了鉴定肠道致病菌，使用了生化试验和血清学确证试验。通过 Kirby-Bauer 纸片扩散药敏试验研究分离株的抗生素耐药模式。
病原菌的发生率包括41.1%的[具体细菌名称1]，其次是41.1%的[具体细菌名称2]，6.7%的肠道致病性[具体细菌名称3]，5.5%的B血清群[具体细菌名称4]，以及5.5%的[具体细菌名称5]。结果显示，共有46例患者有关于[具体细菌名称6]培养的医嘱，样本中未分离出[具体细菌名称6]。所研究的分离株对甲氧苄啶-磺胺甲恶唑和头孢曲松的耐药性最高（88.3%），治疗患者最有效的抗生素是环丙沙星，敏感性为86%。
分离株对抗生素的敏感性不同，这表明早期识别感染病原体并选择正确的抗生素治疗对改善胃肠道感染和预防感染传播有效。
